Tailor-made Antibodies
and Tools for Life Science
Home|||||Technical Support

Hacd 3 antibody - 352 003

Hacd3 is involved in VLCFA synthesis
Rabbit polyclonal purified antibody
Cat. No.: 352 003
Amount: 50 µg
Price: $370.00
Cat. No. 352 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: not tested yet
IHC: not tested yet
IHC-P: not tested yet
Immunogen Recombinant protein corresponding to AA 1 to 149 from rat Hacd3 (UniProt Id: D4ABI7)
Reactivity Reacts with: rat (D4ABI7), mouse (Q8K2C9).
Other species not tested yet.
Specificity Specific for Hacd 3.
Data sheet 352_003.pdf
Cat. No.: 352 003
Amount: 50 µg
Price: $370.00
Background
Very long-chain fatty acids are produced through a four-step cycle. Hacd 3 the very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of two carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. The enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.