Cat. No.: 326 014
Amount: 100 µl
Price:
$370.00
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| Cat. No. 326 014 |
100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Immunogen | Synthetic peptide corresponding to residues near the carboxy terminus of mouse Doublecortin (UniProt Id: Q6PGI2) |
| Reactivity |
Reacts with: mouse (O88809). Other species not tested yet. |
| Data sheet | 326_014.pdf |
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Doublecortin or DCX seems to be required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. Mutations in the gene encoding this protein have been linked to the double cortex syndrome.
Doublecortin is highly expressed in neuronal cells of fetal brain but absent from other tissues. In the adult dentate gyrus it is only expressed in cells contributing to adult neurogenesis.
For more information on protein expression pattern, please refer to the overview image in our SYSY Antibodies ATLAS.