Tailor-made Antibodies
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Tau antibody - 314 006

Tau is a neuronal microtubule associated protein
Chicken polyclonal IgY fraction
Cat. No.: 314 006
Amount: 200 µl
Price: $360.00
Cat. No. 314 006 200 µl antibody, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: 1 : 500 gallery  
IHC-P: 1 : 500 gallery  
Immunogen Recombinant protein corresponding to the N-terminal half of mouse Tau-D (UniProt Id: P10637-5)
Reactivity Reacts with: rat, mouse (P10637-5).
Other species not tested yet.
Specificity This antibody binds phosphorylated and non-phosphorylated tau proteins. The sequence used for immunization is present in all splice variants except human TauA (UniProt Id: P10636-3).
Matching control protein/peptide 314-0P
Remarks

For human tissue cat.no. 314 012 and 314 111 are highly recommended.

Data sheet 314_006.pdf

References for Tau - 314 006

Spatiotemporal analysis of axonal autophagosome-lysosome dynamics reveals limited fusion events and slow maturation.
Cason SE, Mogre SS, Holzbaur ELF, Koslover EF
Molecular biology of the cell (2022) 3313: ar123. 314 006 ICC; tested species: rat
Cat. No.: 314 006
Amount: 200 µl
Price: $360.00
Spatiotemporal analysis of axonal autophagosome-lysosome dynamics reveals limited fusion events and slow maturation.
Cason SE, Mogre SS, Holzbaur ELF, Koslover EF
Molecular biology of the cell (2022) 3313: ar123. 314 006 ICC; tested species: rat
Background

There are two major classes of heat stable microtubule associated proteins (MAPS): MAP 2 (280 kD), and tau (55-65 kD). Both protein classes are involved in the regulation of microtubule polymerization in cells. Tau is a neuronal protein that mainly localizes to axons. Hyperphosphorylated tau has been shown to be a major element of paired helical filaments in Alzheimer's disease.