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beta-Actin antibody - 251 006

beta-Actin is a major constituent of the cytoskeleton
Polyclonal chicken purified antibody
Cat. No.: 251 006
Amount: 50 µg
Price: $370.00
Cat. No. 251 006 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: 1 : 1000 up to 1 : 2000 AP staining gallery  
IP: not tested yet
ICC: 1 : 500 up to 1 : 1000 gallery  
IHC: 1 : 500 up to 1 : 1000 gallery  
IHC-P/FFPE: not tested yet
Immunogen Synthetic peptide corresponding to AA 2 to 16 from mouse β-Actin (UniProt Id: P60710)
Reactivity Reacts with: rat (P60711), mouse (P60710), human (P60709), grashopper, zebrafish, C. elegans.
Other species not tested yet.
Specificity May cross-react to α- and γ-actin due to sequence homology.
Data sheet 251_006.pdf
Cat. No.: 251 006
Quantity: 50 µg
Price: $370.00
Background
The two major cytoskeletal proteins involved in cell motility are myosin and actin. Monomeric actin is a globular protein that is expressed in all eukaryotic cells. Actin is the major subunit of microfilaments, a major component of the cytoskeleton, and of thin filaments, part of the contractile apparatus in muscle cells.
Actin is involved in many cellular processes including cell motility, maintenance of cell shape, and organelle trafficking.
Three main groups of actin have been identified. α-actins are found in muscle tissues whereas β- and γ-actins co-exist in most cell types as components of the cytoskeleton.