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GluN2A/B antibody - 244 004

GluN2A and B are subunits of ionotropic NMDA type glutamate receptors
Guinea pig polyclonal antiserum
Cat. No.: 244 004
Amount: 100 µl
Price: $365.00
Cat. No. 244 004 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: not tested yet
IHC: not tested yet
IHC-P: not tested yet
Immunogen Synthetic peptide corresponding to AA 1448 to 1464 from mouse GluN2A (UniProt Id: P35436)
Reactivity Reacts with: rat (Q00959, Q00960), mouse (P35436, Q01097).
Other species not tested yet.
Specificity Cross-reacts to GluN 2B due to sequence homology.
Matching control protein/peptide 244-0P
Data sheet 244_004.pdf
Cat. No.: 244 004
Amount: 100 µl
Price: $365.00
Background

GluNs (NMDA-receptors) represent a class of glutamate receptors that are of central importance in synaptic plasticity. Multiple NMDA receptor subtypes exist: GluN 1 and GluN 2 A-D. GluN 1 is the most important as it is required for activity. NMDA-receptors allow Ca2+ influx and are thought to trigger Ca2+ dependent postsynaptic processes involved in long term potentiation and depression.