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SynCAM3 antibody - 243 303

SynCAMs are synaptic adhesion molecules of the Ig superfamily
Rabbit polyclonal purified antibody
Cat. No.: 243 303
Amount: 50 µg
Price: $375.00
Cat. No. 243 303 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: not tested yet
IHC: not tested yet
IHC-P: not tested yet
Immunogen Synthetic peptide corresponding to AA 171 to 185 from mouse SynCAM3 (UniProt Id: Q99N28)
Reactivity Reacts with: rat (Q1WIM3), mouse (Q99N28).
Other species not tested yet.
Matching control protein/peptide 243-3P
Data sheet 243_303.pdf
Cat. No.: 243 303
Amount: 50 µg
Price: $375.00
Background

Development of synapses involves transsynaptic interactions of dedicated synaptic adhesion molecules like neuroligins, neurexins and synCAMs (Synaptic cell adhesion molecules). Four SynCAM isoforms have been described so far. All share a common domain structure and contain three extracellular Ig domains, a single transmembrane region, and a short COOH-terminal cytoplasmic tail.
SynCAM 2 has been shown to be associated to myelinated axons and synCAM 3 can serve as a receptor for herpes viruses.