Tailor-made Antibodies
and Tools for Life Science
Home|||||Technical Support

Claudin11 antibody - 241 003

Claudin11 is an oligodendrocyte specific protein
Rabbit polyclonal purified antibody
Cat. No.: 241 003
Amount: 50 µg
Price: $375.00
Cat. No. 241 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) (see remarks) gallery  
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: 1 : 500 gallery  
IHC-P: 1 : 200 up to 1 : 500 gallery  
Immunogen Synthetic peptide corresponding to AA 188 to 207 from rat Claudin11 (UniProt Id: Q99P82)
Reactivity Reacts with: human (O75508), rat (Q99P82), mouse (Q60771), cow, pig.
Other species not tested yet.
Matching control protein/peptide 241-0P
Remarks

WB: Moderate heating (50°C) of samples prior SDS-PAGE improves signal strength.

Data sheet 241_003.pdf

References for Claudin11 - 241 003

Immunosignals of Oligodendrocyte Markers and Myelin-Associated Proteins Are Critically Affected after Experimental Stroke in Wild-Type and Alzheimer Modeling Mice of Different Ages.
Michalski D, Keck AL, Grosche J, Martens H, Härtig W
Frontiers in cellular neuroscience (2018) 12: 23. 241 003 IHC; tested species: mouse
Cat. No.: 241 003
Amount: 50 µg
Price: $375.00
Immunosignals of Oligodendrocyte Markers and Myelin-Associated Proteins Are Critically Affected after Experimental Stroke in Wild-Type and Alzheimer Modeling Mice of Different Ages.
Michalski D, Keck AL, Grosche J, Martens H, Härtig W
Frontiers in cellular neuroscience (2018) 12: 23. 241 003 IHC; tested species: mouse
Background
Claudin 11, also known as Oligodendrocyte specific protein (OSP), is one of the most abundant components of CNS myelin where it locates to the interlamellar strands in myelin sheaths. To date more than 20 members of the claudin family have been identified. They are expressed in epithelial and endothelial cells in all tight junction bearing tissues. Claudins share a common transmembrane topology with 4 transmembrane spanning domains and two extracellular loops.