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GABA-A receptor alpha2 antibody extracellular - 224 111

GABA-A receptors are involved in inhibitory neurotransmission
Mouse monoclonal purified IgM
Cat. No.: 224 111
Amount: 100 µg
Price: $415.00
Cat. No. 224 111 100 µg purified IgM, lyophilized. Azide was added before lyophilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: not recommended
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: not recommended
IHC-P: not tested yet
Clone 7H4
Subtype IgM (κ light chain)
Immunogen Synthetic peptide corresponding to AA 29 to 37 from rat GABA-A receptor α2 (UniProt Id: P23576)
Reactivity Reacts with: rat (P23576), mouse (P26048).
Other species not tested yet.
Matching control protein/peptide 224-1P
Data sheet 224_111.pdf
Cat. No.: 224 111
Amount: 100 µg
Price: $415.00
Background

Gamma-aminobutyric acid type A (GABA-A) receptors mediate the majority of inhibitory neurotransmission in the brain. These receptor proteins are ligand gated chloride ion channels and consist of a pentameric combination of different subunits (alpha, beta, gamma, delta, epsilon and rho). The resulting heterogenous population of GABA-A receptor subtypes are expressed throughout the brain with specific cellular and subcellular expression patterns.