Tailor-made Antibodies
and Tools for Life Science
Home|||||Technical Support
Server maintenance: The maintenance will start Friday, 11.10.24 at 15:00 CEST and will last about an hour. During this time the website will not be available.

Calretinin antibody - 214 308

Calretinin is a vitamin D-dependent calcium binding protein
Guinea pig monoclonal recombinant IgG
Cat. No.: 214 308
Amount: 50 µg
Price: $415.00
Cat. No. 214 308 50 µg purified recombinant IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 500 up to 1 : 1000 (AP-staining) gallery  
IP: not tested yet
ICC: 1 : 500 up to 1 : 2000 gallery  
IHC: 1 : 500 gallery  
IHC-P: not tested yet
IHC-G: 1 : 500 gallery  
Clone Gp37C9
Subtype IgG2 (κ light chain)
Immunogen Full-length recombinant mouse Calretinin (UniProt Id: Q08331)
Reactivity Reacts with: rat (P47728), mouse (Q08331), human (P22676), zebrafish.
Other species not tested yet.
Matching control protein/peptide 214-1P
Remarks

This antibody is a chimeric antibody based on the monoclonal mouse antibody clone 37C9. The constant regions of the heavy and light chains have been replaced by guinea pig specific sequences. Therefore, the antibody can be used with standard anti-guinea pig secondary reagents. The antibody has been expressed in mammalian cells.

Data sheet 214_308.pdf
Cat. No.: 214 308
Amount: 50 µg
Price: $415.00
Background

Two isoforms of the vitamin D-dependent Ca-binding proteins have been described so far: Calretinin, also referred to as calbindin D29k, calbindin 2, CALB 2, CAL 2, and CAB 29, and calbindin D28k. These proteins are expressed in cells that have to handle a high calcium influx such as brain, bone, teeth, inner ear and others. Calbindins are believed to regulate cellular activity by suppressing or buffering intracellur calcium.