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Densin 180 antibody - 189 003

Densin180 is a PSD protein
Rabbit polyclonal purified antibody
Cat. No.: 189 003
Amount: 50 µg
Price: $450.00
Cat. No. 189 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: yes (see remarks)
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: not tested yet
IHC-P/FFPE: not tested yet
Immunogen Synthetic peptide corresponding to AA 877 to 891 from rat Densin 180 (UniProt Id: P70587)
Reactivity Reacts with: rat (P70587), mouse (Q80TE7).
Other species not tested yet.
Specificity Specific for densin 180.
Remarks

WB: The crude antiserum (cat. no. 189 002) is recommended for WB (stronger signals).

Data sheet 189_003.pdf

References for Densin 180 - 189 003

Ca(V)1 and Ca(V)2 channels engage distinct modes of Ca(2+) signaling to control CREB-dependent gene expression.
Wheeler DG, Groth RD, Ma H, Barrett CF, Owen SF, Safa P, Tsien RW
Cell (2012) 1495: 1112-24. 189 003 ICC; tested species: rat
Cat. No.: 189 003
Quantity: 50 µg
Price: $450.00
Ca(V)1 and Ca(V)2 channels engage distinct modes of Ca(2+) signaling to control CREB-dependent gene expression.
Wheeler DG, Groth RD, Ma H, Barrett CF, Owen SF, Safa P, Tsien RW
Cell (2012) 1495: 1112-24. 189 003 ICC; tested species: rat
Background
Densin is a 180 kDa transmembrane glycoprotein which belongs to the LAP family [leucine-rich repeat (LRR) and PDZ] family, characterized by an LRR near the N-terminus and one or more PDZ domains at the C-terminus. Several developmentally regulated splice variants and protein-protein interactions with CamKII and nephrin have been described. The protein locates to the post-synaptic density (PSD) in nerve cells but has also been shown to be expressed in glomerular podocytes in kidney.
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