|Cat. No. 185-0P||
100 µg peptide, lyophilized. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Control peptides should be stored at -20°C when still lyophilized!
|Immunogen||Synthetic peptide corresponding to AA 1416 to 1430 from rat CASKIN1 (UniProt Id: Q8VHK2)|
|Recommended dilution||Optimal concentrations should be determined by the end-user.|
|Matching antibodies||185 002, 185 003|
This control peptide consists of the synthetic peptide (aa 1416 - 1430 of CASKIN 1) that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of peptide needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen.
The complex of the multi-adaptor-proteins CASK, Veli and Mint is conserved across kingdoms. CASKIN 1 is a novel CASK interaction partner that binds to its Cam Kinase domain and competes with Mint so that alternative complexes can be formed. Four different splice variants have been identified so far.