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GluA2 antibody - 182 117

GluAs are ionotropic glutamate receptors involved in rapid excitatory neurotransmission
Rat monoclonal purified IgG
Cat. No.: 182 117
Amount: 100 µg
Price: $415.00
Cat. No. 182 117 100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 500 up to 1 : 1000 gallery  
IHC: 1 : 500 gallery  
IHC-P: 1 : 200 gallery  
Clone SY-4G7
Subtype IgG2a (λ light chain)
Immunogen Recombinant protein corresponding to residues near the carboxy terminus of rat GluA2. (UniProt Id: P19491)
Reactivity Reacts with: mouse (P23819), rat (P19491).
Other species not tested yet.
Matching control protein/peptide 182-1P
Data sheet 182_117.pdf
Cat. No.: 182 117
Amount: 100 µg
Price: $415.00
Background

Ionotropic glutamate receptors (iGluRs) mediate rapid excitatory neurotransmission in the mammalian CNS. They can be subdivided into three major groups, the AMPA/GluA, NMDA/GluN and kainate/GluK receptors (KARs). mRNAs coding for glutamate receptors are substrates for an adenosine deaminase acting on RNA (ADAR) that increases the diversity of these proteins.
Glutamate receptors of the AMPA subtype are monovalent cation channels and are composed of the four AMPA subunits GluA 1, GluA 2, GluA 3, and GluA 4.