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GluA1 protein - 182-0P

GluAs are ionotropic glutamate receptors involved in rapid excitatory neurotransmission
control protein
Cat. No.: 182-0P
Amount: 100 µg
Price: $105.00
Cat. No. 182-0P 100 µg protein, lyophilized. For reconstitution add 100 µl H2O to get a 1mg/ml solution in TBS. Then aliquot and store at -20°C to -80°C until use.
Control proteins should be stored at +4°C when still lyophilized. Do not freeze!
Immunogen Recombinant protein corresponding to AA 829 to 907 from mouse GluA1 (UniProt Id: P23818)
Recommended dilution Optimal concentrations should be determined by the end-user.
Matching antibodies 182 003

This control protein consists of the recombinant protein (aa 828 - 906 of mouse GluA 1) that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of protein needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen.

Data sheet 182-0p.pdf
Cat. No.: 182-0P
Amount: 100 µg
Price: $105.00

Ionotropic glutamate receptors (iGluRs) mediate rapid excitatory neurotransmission in the mammalian CNS. They can be subdivided into three major groups, the AMPA/GluA, NMDA/GluN and kainate/GluK receptors (KARs). mRNAs coding for glutamate receptors are substrates for an adenosine deaminase acting on RNA (ADAR) that increases the diversity of these proteins.
Glutamate receptors of the AMPA subtype are monovalent cation channels and are composed of the four AMPA subunits GluA 1, GluA 2, GluA 3, and GluA 4.