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Shank2 antibody - 162 206

Shanks are multidomain proteins of the postsynaptic density
Chicken polyclonal purified antibody
Cat. No.: 162 206
Amount: 50 µg
Price: $380.00
Cat. No. 162 206 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 up to 1 : 2000 gallery  
IP: not tested yet
ICC: 1 : 500 up to 1 : 1000 gallery  
IHC: not tested yet
IHC-P: not tested yet
Immunogen Recombinant protein corresponding to residues near the carboxy terminus of rat Shank2 (UniProt Id: Q9QX74)
Reactivity Reacts with: rat (Q9QX74), mouse (Q80Z38).
Other species not tested yet.
Specificity Specific for Shank 2 with weak cross-reactivity to Shank 1 and Shank 3.
Data sheet 162_206.pdf
Cat. No.: 162 206
Amount: 50 µg
Price: $380.00
Background

Shank1, 2 and 3 are major proteins of the postsynaptic density (PSD). They are composed of several protein-protein interaction domains like PDZ-, homer- and ABP1-binding domains which allow them to crosslink ionotopic and metabotropic glutamate receptor complexes with each other and to the actin-cytoskeleton.