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Shank 2 - 162 204

Multidomain proteins of the postsynaptic density
Polyclonal Guinea pig antiserum
Cat. No.: 162 204
Amount: 100 µl
Price: 350.00 €
Cat. No. 162 204 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 up to 1 : 5000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 1000 up to 1 : 2000 gallery  
IHC: 1 : 500 gallery  
IHC-P/FFPE: 1 : 500
Immunogen Recombinant protein corresponding to AA 1042 to 1475 from rat Shank2 (UniProt Id: Q9QX74)
Reactivity Reacts with: rat (Q9QX74), mouse (Q80Z38).
Other species not tested yet.
Specificity Specific for shank 2. K.O. PubMed: 29970987
Data sheet 162_204.pdf

References for Shank 2 - 162 204

Dendritic spine morphology and memory formation depend on postsynaptic Caskin proteins.
Bencsik N, Pusztai S, Borbély S, Fekete A, Dülk M, Kis V, Pesti S, Vas V, Szűcs A, Buday L, Schlett K, et al.
Scientific reports (2019) 91: 16843. 162 204 WB, IP, ICC; tested species: mouse
Dendritic spine morphology and memory formation depend on postsynaptic Caskin proteins.
Bencsik N, Pusztai S, Borbély S, Fekete A, Dülk M, Kis V, Pesti S, Vas V, Szűcs A, Buday L, Schlett K, et al.
Scientific reports (2019) 91: 16843. 162 204 WB, IP, ICC; tested species: mouse
Serine-Arginine Protein Kinase SRPK2 Modulates the Assembly of the Active Zone Scaffolding Protein CAST1/ERC2.
Arancibia D, Lira M, Cruz Y, Barrera DP, Montenegro-Venegas C, Godoy JA, Garner CC, Inestrosa NC, Gundelfinger ED, Zamorano P, Torres VI, et al.
Cells (2019) 811: . 162 204 ICC; tested species: rat
An Autaptic Culture System for Standardized Analyses of iPSC-Derived Human Neurons.
Rhee HJ, Shaib AH, Rehbach K, Lee C, Seif P, Thomas C, Gideons E, Guenther A, Krutenko T, Hebisch M, Peitz M, et al.
Cell reports (2019) 277: 2212-2228.e7. 162 204 ICC; tested species: human
Dendritic spine morphology and memory formation depend on postsynaptic Caskin proteins.
Bencsik N, Pusztai S, Borbély S, Fekete A, Dülk M, Kis V, Pesti S, Vas V, Szűcs A, Buday L, Schlett K, et al.
Scientific reports (2019) 91: 16843. 162 204 WB, IP, ICC; tested species: mouse
The Exocyst Component Exo70 Modulates Dendrite Arbor Formation, Synapse Density, and Spine Maturation in Primary Hippocampal Neurons.
Lira M, Arancibia D, Orrego PR, Montenegro-Venegas C, Cruz Y, García J, Leal-Ortiz S, Godoy JA, Gundelfinger ED, Inestrosa NC, Garner CC, et al.
Molecular neurobiology (2018) : . 162 204 ICC; tested species: rat
Inositol polyphosphate multikinase mediates extinction of fear memory.
Park J, Longo F, Park SJ, Lee S, Bae M, Tyagi R, Han JH, Kim S, Santini E, Klann E, Snyder SH, et al.
Proceedings of the National Academy of Sciences of the United States of America (2019) : . 162 204 IHC; tested species: mouse
Localization of group II and III metabotropic glutamate receptors at pre- and postsynaptic sites of inner hair cell ribbon synapses.
Klotz L, Wendler O, Frischknecht R, Shigemoto R, Schulze H, Enz R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2019) : fj201901543R. 162 204 IHC; tested species: mouse
Cell-Type-Specific Shank2 Deletion in Mice Leads to Differential Synaptic and Behavioral Phenotypes.
Kim R, Kim J, Chung C, Ha S, Lee S, Lee E, Yoo YE, Kim W, Shin W, Kim E
The Journal of neuroscience : the official journal of the Society for Neuroscience (2018) 3817: 4076-4092. 162 204 IHC; tested species: mouse
Shank2 Deletion in Parvalbumin Neurons Leads to Moderate Hyperactivity, Enhanced Self-Grooming and Suppressed Seizure Susceptibility in Mice.
Lee S, Lee E, Kim R, Kim J, Lee S, Park H, Yang E, Kim H, Kim E
Frontiers in molecular neuroscience (2018) 11: 209. 162 204 IHC; KO verified; tested species: mouse
Cat. No.: 162 204
Quantity: 100 µl
Price: 350.00 €
Dendritic spine morphology and memory formation depend on postsynaptic Caskin proteins.
Bencsik N, Pusztai S, Borbély S, Fekete A, Dülk M, Kis V, Pesti S, Vas V, Szűcs A, Buday L, Schlett K, et al.
Scientific reports (2019) 91: 16843. 162 204 WB, IP, ICC; tested species: mouse
Dendritic spine morphology and memory formation depend on postsynaptic Caskin proteins.
Bencsik N, Pusztai S, Borbély S, Fekete A, Dülk M, Kis V, Pesti S, Vas V, Szűcs A, Buday L, Schlett K, et al.
Scientific reports (2019) 91: 16843. 162 204 WB, IP, ICC; tested species: mouse
Serine-Arginine Protein Kinase SRPK2 Modulates the Assembly of the Active Zone Scaffolding Protein CAST1/ERC2.
Arancibia D, Lira M, Cruz Y, Barrera DP, Montenegro-Venegas C, Godoy JA, Garner CC, Inestrosa NC, Gundelfinger ED, Zamorano P, Torres VI, et al.
Cells (2019) 811: . 162 204 ICC; tested species: rat
An Autaptic Culture System for Standardized Analyses of iPSC-Derived Human Neurons.
Rhee HJ, Shaib AH, Rehbach K, Lee C, Seif P, Thomas C, Gideons E, Guenther A, Krutenko T, Hebisch M, Peitz M, et al.
Cell reports (2019) 277: 2212-2228.e7. 162 204 ICC; tested species: human
Dendritic spine morphology and memory formation depend on postsynaptic Caskin proteins.
Bencsik N, Pusztai S, Borbély S, Fekete A, Dülk M, Kis V, Pesti S, Vas V, Szűcs A, Buday L, Schlett K, et al.
Scientific reports (2019) 91: 16843. 162 204 WB, IP, ICC; tested species: mouse
The Exocyst Component Exo70 Modulates Dendrite Arbor Formation, Synapse Density, and Spine Maturation in Primary Hippocampal Neurons.
Lira M, Arancibia D, Orrego PR, Montenegro-Venegas C, Cruz Y, García J, Leal-Ortiz S, Godoy JA, Gundelfinger ED, Inestrosa NC, Garner CC, et al.
Molecular neurobiology (2018) : . 162 204 ICC; tested species: rat
Inositol polyphosphate multikinase mediates extinction of fear memory.
Park J, Longo F, Park SJ, Lee S, Bae M, Tyagi R, Han JH, Kim S, Santini E, Klann E, Snyder SH, et al.
Proceedings of the National Academy of Sciences of the United States of America (2019) : . 162 204 IHC; tested species: mouse
Localization of group II and III metabotropic glutamate receptors at pre- and postsynaptic sites of inner hair cell ribbon synapses.
Klotz L, Wendler O, Frischknecht R, Shigemoto R, Schulze H, Enz R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2019) : fj201901543R. 162 204 IHC; tested species: mouse
Cell-Type-Specific Shank2 Deletion in Mice Leads to Differential Synaptic and Behavioral Phenotypes.
Kim R, Kim J, Chung C, Ha S, Lee S, Lee E, Yoo YE, Kim W, Shin W, Kim E
The Journal of neuroscience : the official journal of the Society for Neuroscience (2018) 3817: 4076-4092. 162 204 IHC; tested species: mouse
Shank2 Deletion in Parvalbumin Neurons Leads to Moderate Hyperactivity, Enhanced Self-Grooming and Suppressed Seizure Susceptibility in Mice.
Lee S, Lee E, Kim R, Kim J, Lee S, Park H, Yang E, Kim H, Kim E
Frontiers in molecular neuroscience (2018) 11: 209. 162 204 IHC; KO verified; tested species: mouse