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SynGAP antibody - 157 003

SynGAP is a synaptic Ras-GTPase activating protein
Rabbit polyclonal purified antibody
Cat. No.: 157 003
Amount: 50 µg
Price: $450.00
Cat. No. 157 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications
 
WB: 1 : 1000 up to 1 : 4000 AP staining gallery  
IP: not tested yet
ICC: 1 : 100 up to 1 : 200 gallery  
IHC: not tested yet
IHC-P: not tested yet
Immunogen Synthetic peptide corresponding to AA 1274 to 1293 from rat SynGAP (UniProt Id: Q9QUH6)
Reactivity Reacts with: rat (Q9QUH6).
Other species not tested yet.
Specificity Recognizes both isofoms SynGAP a and b.
Matching control protein/peptide 157-0P
Data sheet 157_003.pdf
Cat. No.: 157 003
Amount: 50 µg
Price: $450.00
Background

SynGAP is an approximately 135 kDa protein which is condensed at the post-synaptic density. A potential interaction partner for this protein is the abundant PDZ domain protein PSD 95.
Three isoforms (a, b and c) of synGAP have been described. The protein is a substrate for calmodulin dependent kinase 2 (CAMK2). Phosphorylation of synGAP reduces its activity, leading to an increased activation of Ras.