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CASK antibody - 150 103

CASK is a MAGUK family protein of the pre-synaptic active zone
Rabbit polyclonal purified antibody
Cat. No.: 150 103
Amount: 50 µg
Price: $450.00
Cat. No. 150 103 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: 1 : 100 up to 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: not tested yet
IHC: not tested yet
IHC-P/FFPE: not tested yet
Immunogen Recombinant protein corresponding to AA 318 to 415 from rat CASK (UniProt Id: Q62915)
Reactivity Reacts with: rat (Q62915), mouse (O70589).
Other species not tested yet.
Specificity Specific for CASK.
Data sheet 150_103.pdf
Cat. No.: 150 103
Quantity: 50 µg
Price: $450.00

CASK, like PSD 95, belongs to the family of membrane associated guanylate kinase homologues (MAGUKs) but contains an additional N-terminal CaM kinase-like domain.
It has been shown to interact with Mint and Veli via its N-terminal domains. PDZ domains are present in all three proteins of the complex. They are free to recruit other proteins like neurexins and syndecans. The complex of CASK, Velis and Mint is conserved across kingdoms and has also been observed in C. elegans.