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VGLUT 3 - 135 208

A new vesicular glutamate transporter
Monoclonal Recombinant rabbit purified IgG
Cat. No.: 135 208
Amount: 50 µg
Price: 415.00 €
Cat. No. 135 208 50 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use.
Applications WB: not tested yet
IP: not tested yet
ICC: not tested yet
IHC: 1 : 500 gallery  
IHC-P/FFPE: 1 : 100 up to 1 : 1000 gallery  
Clone Rb57A8
Subtype IgG1 (κ light chain)
Immunogen Synthetic peptide corresponding to AA 563 to 601 from mouse VGLUT3 (UniProt Id: Q8BFU8)
Reactivity Reacts with: rat (Q7TSF2), mouse (Q8BFU8).
Other species not tested yet.
Specificity Specific for VGLUT 3
Remarks

This antibody is a chimeric antibody based on the monoclonal mouse antibody clone 57A8. The constant regions of the heavy and light chains have been replaced by rabbit specific sequences. Therefore, the antibody can be used with standard anti-rabbit secondary reagents. The antibody has been expressed in mammalian cells.

Data sheet 135_208.pdf
Cat. No.: 135 208
Quantity: 50 µg
Price: 415.00 €
Background

The vesicular glutamate transporter 3 VGLUT 3 is closely related to VGLUT 1 and VGLUT 2 by sequence similarity. However, VGLUT 3 defines a new distinct glutamatergic system in brain which is strictly seperated from VGLUT 1 and VGLUT 2 synapses. Co-localization with the acetylcholine transporter VAChT and the monoamine transporter 2 VMaT 2 has been observed.