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Neuroligin 1/2/3/4 antibody - 129 211

Neuroligins are postsynaptic cell adhesion molecules
Mouse monoclonal purified IgG
Cat. No.: 129 211
Amount: 100 µg
Price: $415.00
Cat. No. 129 211 100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 200 up to 1 : 500 gallery  
IHC: not recommended
IHC-P: not tested yet
Clone 87H9
Subtype IgG1 (κ light chain)
Immunogen Recombinant protein corresponding to AA 710 to 824 from mouse Neuroligin3 (UniProt Id: Q8BYM5)
Epitop Epitop: AA 608 to 722 from mouse Neuroligin3 (UniProt Id: Q8BYM5)
Reactivity Reacts with: rat (Q62765, Q62888, Q62889, ), mouse (Q99K10, Q69ZK9, Q8BYM5, B0F2B4).
Other species not tested yet.
Specificity WB: Recognizes neuroligin 2 and 3.
ICC: Stains predominantly neuroligin 2 in cultured hippocampus neurons. Detects transiently expressed GFP fusion proteins comprising the cytoplasmic tails of neuroligins 1-4. K.O.
Matching control protein/peptide 129-1P
Data sheet 129_211.pdf

References for Neuroligin 1/2/3/4 - 129 211

Physical Interactions and Functional Relationships of Neuroligin 2 and Midbrain Serotonin Transporters.
Ye R, Quinlan MA, Iwamoto H, Wu HH, Green NH, Jetter CS, McMahon DG, Veestra-VanderWeele J, Levitt P, Blakely RD
Frontiers in synaptic neuroscience (2015) 7: 20. 129 211 WB; tested species: mouse
Effects of chronic exposure to haloperidol, olanzapine or lithium on SV2A and NLGN synaptic puncta in the rat frontal cortex.
Halff EF, Cotel MC, Natesan S, McQuade R, Ottley CJ, Srivastava DP, Howes OD, Vernon AC
Behavioural brain research (2021) 405: 113203. 129 211 IHC; tested species: rat
A novel synaptic junction preparation for the identification and characterization of cleft proteins.
Burch A, Tao-Cheng JH, Dosemeci A
PloS one (2017) 123: e0174895. 129 211 EM; tested species: rat
Cat. No.: 129 211
Amount: 100 µg
Price: $415.00
Physical Interactions and Functional Relationships of Neuroligin 2 and Midbrain Serotonin Transporters.
Ye R, Quinlan MA, Iwamoto H, Wu HH, Green NH, Jetter CS, McMahon DG, Veestra-VanderWeele J, Levitt P, Blakely RD
Frontiers in synaptic neuroscience (2015) 7: 20. 129 211 WB; tested species: mouse
Effects of chronic exposure to haloperidol, olanzapine or lithium on SV2A and NLGN synaptic puncta in the rat frontal cortex.
Halff EF, Cotel MC, Natesan S, McQuade R, Ottley CJ, Srivastava DP, Howes OD, Vernon AC
Behavioural brain research (2021) 405: 113203. 129 211 IHC; tested species: rat
A novel synaptic junction preparation for the identification and characterization of cleft proteins.
Burch A, Tao-Cheng JH, Dosemeci A
PloS one (2017) 123: e0174895. 129 211 EM; tested species: rat
Background

Neuroligins form a family of postsynaptic cell surface molecules that interact with β-neurexins. They are 110-120 kDa polypeptides with homology to acetylcholine esterase. Neuroligin 1 and neuroligin 3 are specifically localized to post-synaptic densities of excitatory synapses whereas neuroligin 2 is found exclusively on inhibitory synapses.
Mutations in neuroligin 3 and neuroligin 4 have been implicated with a rare, heritable form of autism.