|Cat. No. 124 302||200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.|
WB: 1 : 1000 (AP staining) gallery
IP: not tested yet
ICC: not tested yet
IHC: not tested yet
IHC-P/FFPE: not tested yet
|Immunogen||Synthetic peptide corresponding to AA 115 to 133 from rat SAP97 (UniProt Id: Q62696)|
Reacts with: rat (Q62696).
No signal: zebrafish.
Other species not tested yet.
|Specificity||Specific for SAP 97.|
|Matching control protein/peptide||124-3P|
SAP 97 (synapse associated protein of 97 kDa, also called DLG 1) like PSD 95 and SAP 102, is a scaffolding protein of the postsynaptic density. It consists of three type-one PDZ domains and binds selectively to the C-terminus of the GluR1 subunit of AMPA receptors.
SAP 97 is probably involved in the clustering of AMPA receptors at the post-synaptic membrane.
It is also expressed in heart, where it has been shown to be involved in the targeting of voltage gated potassium channels to subpopulations of lipid rafts.