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SY SY - Synaptic Systems SY SY - Synaptic Systems

Sra 1

A protein involved in the initiation of actin polymerization

References SySy Sra 1 antibodies

Sra-1 interacts with Kette and Wasp and is required for neuronal and bristle development in Drosophila.
Bogdan S, Grewe O, Strunk M, Mertens A, Klämbt C
Development (Cambridge, England) (2004) 13116: 3981-9.
Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation.
Steffen A, Rottner K, Ehinger J, Innocenti M, Scita G, Wehland J, Stradal TE
The EMBO journal (2004) 234: 749-59.
p140Sra-1 (specifically Rac1-associated protein) is a novel specific target for Rac1 small GTPase.
Kobayashi K, Kuroda S, Fukata M, Nakamura T, Nagase T, Nomura N, Matsuura Y, Yoshida-Kubomura N, Iwamatsu A, Kaibuchi K
The Journal of biological chemistry (1998) 2731: 291-5.
WAVE2-Abi2 complex controls growth cone activity and regulates the multipolar-bipolar transition as well as the initiation of glia-guided migration.
Xie MJ, Yagi H, Kuroda K, Wang CC, Komada M, Zhao H, Sakakibara A, Miyata T, Nagata K, Oka Y, Iguchi T, et al.
Cerebral cortex (New York, N.Y. : 1991) (2013) 236: 1410-23. 309 011 WB; tested species: mouse
Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice.
Bozdagi O, Sakurai T, Dorr N, Pilorge M, Takahashi N, Buxbaum JD
PloS one (2012) 78: e42422. 309 011 WB; tested species: mouse
Filopodia formation in the absence of functional WAVE- and Arp2/3-complexes.
Steffen A, Faix J, Resch GP, Linkner J, Wehland J, Small JV, Rottner K, Stradal TE
Molecular biology of the cell (2006) 176: 2581-91. 309 011 WB
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Phone: +49 (0)551/505 56-0 | Internet: | E-Mail: