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A transcription factor involved in neuronal differentiation

General Information

The Special AT-rich sequence-binding protein 2 or SATB 2 is a transcription factor required for the initiation of the genetic program for the upper-layer neurons (UL1).
Together with Ctip 2, Coup-TFI, and Fezf 2 it is involved in the fine tuned sequential formation and specification of the different excitatory neuron populations forming the definitive six-layered cortical structure.
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Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: | E-Mail: