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Synaptotagmin 3

A synaptotagmin enriched in synaptosomal membranes

General Information

Up to now at least 17 synaptotagmins have been identified. Like other proteins of this family synaptotagmin 3 is composed of a vesicular, a transmembrane and two C2 domains.
Synaptotagmin 3 is expressed in brain, where it localizes to synaptic plasma membranes, and also in non-neuronal cells. In pancreatic islet β-cells it is involved in Ca2+ triggered insulin secretion, and in basophilic leukemia mast cells (RBL-cells) in transport events to the perinuclear endocytic recycling compartment.
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Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: http://www.sysy.com | E-Mail: sales@sysy.com