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SY SY - Synaptic Systems SY SY - Synaptic Systems

Synaptophysin 1 - 101 008

Major synaptic vesicle membrane protein; neuroendocrine tumor marker

Recombinant rabbit purified IgG
415.00 USD
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Cat. No. 101 008 50 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 up to 1 : 10000 (AP staining) gallery  
IP: yes
ICC: 1 : 500 up to 1 : 1000 gallery  
IHC: 1 : 500 gallery  
IHC-P/FFPE: 1 : 500 gallery  
Clone Rb7.2
Subtype IgG1 (κ light chain)
Immunogen Recombinant protein corresponding to AA 1 to 307 from rat Synaptophysin1 (UniProt Id: P07825)
Epitop Epitop: AA 219 to 307 from rat Synaptophysin1 (UniProt Id: P07825)
Reactivity Reacts with: human (P08247), rat (P07825), mouse (Q62277), mammals.
Weaker signal: zebrafish, other vertebrates.
Other species not tested yet.
Specificity Specific for synaptophysin 1, no cross-reactivity to other synaptophysins. (K.O. verified)
Remarks

This antibody is a chimeric antibody based on the well known monoclonal mouse antibody clone 7.2. The constant regions of the heavy and light chains have been replaced by rabbit specific sequences. Therefore, the antibody can be used with standard anti-rabbit secondary reagents. The antibody has been expressed in mammalian cells.
Synaptophysin 1 is widely used as marker for nerve terminals and neuroendocrine tumors. For still unknown reason, neuronal synaptophysin is better recognized than neuroendocrine synaptophysin. If this is a problem, the polyclonal rabbit antibody, cat. no. 101 002, is recommended.

Datasheet 101_008.pdf


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Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: http://www.sysy.com | E-Mail: sales@sysy.com