Tailor-made Antibodies
and Tools for Life Science
Home|||||Technical Support

Neuroligin2 antibody - 129 205 K.O.

Neuroligins are postsynaptic cell adhesion molecules
Guinea pig polyclonal purified antibody
Cat. No.: 129 205
Amount: 50 µg
Price: $460.00
Cat. No. 129 205 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 100 up to 1 : 500 gallery  
IHC: 1 : 500 (see remarks) gallery  
IHC-P: not tested yet
EM: yes
Immunogen Synthetic peptide corresponding to AA 750 to 767 from rat Neuroligin2 (UniProt Id: Q62888)
Reactivity Reacts with: rat (Q62888), mouse (Q69ZK9).
Other species not tested yet.
Specificity K.O. validated
Remarks

IHC: This antibody requires mild fixation.

Data sheet 129_205.pdf

References for Neuroligin2 - 129 205

Vision-dependent specification of cell types and function in the developing cortex.
Cheng S, Butrus S, Tan L, Xu R, Sagireddy S, Trachtenberg JT, Shekhar K, Zipursky SL
Cell (2022) 1852: 311-327.e24. 129 205 IHC; tested species: mouse
Vangl2 in the Dentate Network Modulates Pattern Separation and Pattern Completion.
Robert BJA, Moreau MM, Dos Santos Carvalho S, Barthet G, Racca C, Bhouri M, Quiedeville A, Garret M, Atchama B, Al Abed AS, Guette C, et al.
Cell reports (2020) 3110: 107743. 129 205 IHC; tested species: mouse
Cat. No.: 129 205
Amount: 50 µg
Price: $460.00
Vision-dependent specification of cell types and function in the developing cortex.
Cheng S, Butrus S, Tan L, Xu R, Sagireddy S, Trachtenberg JT, Shekhar K, Zipursky SL
Cell (2022) 1852: 311-327.e24. 129 205 IHC; tested species: mouse
Vangl2 in the Dentate Network Modulates Pattern Separation and Pattern Completion.
Robert BJA, Moreau MM, Dos Santos Carvalho S, Barthet G, Racca C, Bhouri M, Quiedeville A, Garret M, Atchama B, Al Abed AS, Guette C, et al.
Cell reports (2020) 3110: 107743. 129 205 IHC; tested species: mouse
Background

Neuroligins form a family of postsynaptic cell surface molecules that interact with β-neurexins. They are 110-120 kDa polypeptides with homology to acetylcholine esterase. Neuroligin 1 and neuroligin 3 are specifically localized to post-synaptic densities of excitatory synapses whereas neuroligin 2 is found exclusively on inhibitory synapses.
Mutations in neuroligin 3 and neuroligin 4 have been implicated with a rare, heritable form of autism.