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SY SY - Synaptic Systems SY SY - Synaptic Systems

Calreticulin Mutation HistoSure®

A neoepitope present in all Calreticulin mutations

References SySy Calreticulin Mutation HistoSure--r-- antibodies

Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2.
Nangalia J, Massie CE, Baxter EJ, Nice FL, Gundem G, Wedge DC, Avezov E, Li J, Kollmann K, Kent DG, Aziz A, et al.
The New England journal of medicine (2013) 36925: 2391-2405.
Somatic mutations of calreticulin in myeloproliferative neoplasms.
Klampfl T, Gisslinger H, Harutyunyan AS, Nivarthi H, Rumi E, Milosevic JD, Them NC, Berg T, Gisslinger B, Pietra D, Chen D, et al.
The New England journal of medicine (2013) 36925: 2379-90.
Calreticulin mutation specific CAL2 immunohistochemistry accurately identifies rare calreticulin mutations in myeloproliferative neoplasms.
Mózes R, Gángó A, Sulák A, Vida L, Reiniger L, Timár B, Krenács T, Alizadeh H, Masszi T, Gaál-Weisinger J, Demeter J, et al.
Pathology (2018) : . HS-315 111-S, HS-315 111-L IHC-P; tested species: human
A new monoclonal antibody (CAL2) detects CALRETICULIN mutations in formalin-fixed and paraffin-embedded bone marrow biopsies.
Stein H, Bob R, Dürkop H, Erck C, Kämpfe D, Kvasnicka HM, Martens H, Roth A, Streubel A
Leukemia (2016) 301: 131-5. HS-315 111-S, HS-315 111-L IHC-P; tested species: human
CAL2 Immunohistochemical Staining Accurately Identifies CALR Mutations in Myeloproliferative Neoplasms.
Nomani L, Bodo J, Zhao X, Durkin L, Loghavi S, Hsi ED
American journal of clinical pathology (2016) 1464: 431-8. HS-315 111-S, HS-315 111-L IHC-P; tested species: human
Mutation specific immunohistochemistry is highly specific for the presence of calreticulin mutations in myeloproliferative neoplasms.
Andrici J, Farzin M, Clarkson A, Sioson L, Sheen A, Watson N, Toon CW, Koleth M, Stevenson W, Gill AJ
Pathology (2016) 484: 319-24. HS-315 111-S, HS-315 111-L IHC-P; tested species: human
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Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: http://www.sysy.com | E-Mail: sales@sysy.com