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Myelin basic protein peptide - 295-0P

MBP is a major component of the myelin sheath
control peptide
Cat. No.: 295-0P
Amount: 100 µg
Price: $105.00
Cat. No. 295-0P 100 µg peptide, lyophilized. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Control peptides should be stored at -20°C when still lyophilized!
Applications
 
Immunogen Synthetic peptide corresponding to AA 105 to 115 from rat MBP (UniProt Id: P02688)
Recommended dilution Optimal concentrations should be determined by the end-user.
Matching antibodies 295 002, 295 003, 295 004
Remarks

This control peptide consists of the synthetic peptide (aa 105-115 of rat MBP 1 unprocessed precursor) that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of peptide needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen.

Data sheet 295-0p.pdf
Cat. No.: 295-0P
Amount: 100 µg
Price: $105.00
Background
The myelin sheath is a multi-layered membrane composed of several proteins like PLP, claudin 11 and myelin basic protein (MBP) which is specific for the nervous system. MBP functions as an insulator and increases the velocity of axonal impulse conduction.
MBP can be subdivided into the classic group consisting of isoforms 4 to 14 and the non-classic group of MBP comprising the Golli MBPs (isoforms 1 to 3). Differential splicing events and optional posttranslational modifications give rise to a wide spectrum of isomers with potentially specialized functions.
Protocols