print page Visit us on Instagram Visit us on Facebook Visit us on Twitter Visit us on LinkedIn
SY SY - Synaptic Systems SY SY - Synaptic Systems

IBA 1

A calcium binding protein specific for microglia

References SySy IBA 1 antibodies

Morphological and ultrastructural features of Iba1-immunolabeled microglial cells in the hippocampal dentate gyrus.
Shapiro LA, Perez ZD, Foresti ML, Arisi GM, Ribak CE
Brain research (2009) 1266: 29-36.
Reduction of Iba1-expressing microglial process density in the hippocampus following electroconvulsive shock.
Jinno S, Kosaka T
Experimental neurology (2008) 2122: 440-7.
A comparison of spinal Iba1 and GFAP expression in rodent models of acute and chronic pain.
Romero-Sandoval A, Chai N, Nutile-McMenemy N, Deleo JA
Brain research (2008) 1219: 116-26.
Expression of Iba1 protein in microglial cells of zitter mutant rat.
Kadowaki T, Nakadate K, Sakakibara S, Hirata K, Ueda S
Neuroscience letters (2007) 4111: 26-31.
Visualization of microglia in living tissues using Iba1-EGFP transgenic mice.
Hirasawa T, Ohsawa K, Imai Y, Ondo Y, Akazawa C, Uchino S, Kohsaka S
Journal of neuroscience research (2005) 813: 357-62.
Microglia/macrophage-specific protein Iba1 binds to fimbrin and enhances its actin-bundling activity.
Ohsawa K, Imai Y, Sasaki Y, Kohsaka S
Journal of neurochemistry (2004) 884: 844-56.
Intracellular signaling in M-CSF-induced microglia activation: role of Iba1.
Imai Y, Kohsaka S
Glia (2002) 402: 164-74.
Macrophage/microglia-specific protein Iba1 enhances membrane ruffling and Rac activation via phospholipase C-gamma -dependent pathway.
Kanazawa H, Ohsawa K, Sasaki Y, Kohsaka S, Imai Y
The Journal of biological chemistry (2002) 27722: 20026-32.
Iba1 is an actin-cross-linking protein in macrophages/microglia.
Sasaki Y, Ohsawa K, Kanazawa H, Kohsaka S, Imai Y
Biochemical and biophysical research communications (2001) 2862: 292-7.
Spermatid-specific expression of Iba1, an ionized calcium binding adapter molecule-1, in rat testis.
Iida H, Doiguchi M, Yamashita H, Sugimachi S, Ichinose J, Mori T, Shibata Y
Biology of reproduction (2001) 644: 1138-46.
Heterogenous immunohistochemical expression of microglia-specific ionized calcium binding adaptor protein (Iba1) in the mouse olfactory bulb.
Okere CO, Kaba H
Brain research (2000) 8771: 85-90.
Involvement of Iba1 in membrane ruffling and phagocytosis of macrophages/microglia.
Ohsawa K, Imai Y, Kanazawa H, Sasaki Y, Kohsaka S
Journal of cell science (2000) 113 ( Pt 17): 3073-84.
Microglia-specific localisation of a novel calcium binding protein, Iba1.
Ito D, Imai Y, Ohsawa K, Nakajima K, Fukuuchi Y, Kohsaka S
Brain research. Molecular brain research (1998) 571: 1-9.
High fat diet treatment impairs hippocampal long-term potentiation without alterations of the core neuropathological features of Alzheimer disease.
Salas IH, Weerasekera A, Ahmed T, Callaerts-Vegh Z, Himmelreich U, D'Hooge R, Balschun D, Saido TC, De Strooper B, Dotti CG
Neurobiology of disease (2018) 113: 82-96. 234 003 WB; tested species: mouse
Distinct in vivo roles of secreted APP ectodomain variants APPsα and APPsβ in regulation of spine density, synaptic plasticity, and cognition.
Richter MC, Ludewig S, Winschel A, Abel T, Bold C, Salzburger LR, Klein S, Han K, Weyer SW, Fritz AK, Laube B, et al.
The EMBO journal (2018) : . 234 003 WB, IHC; tested species: mouse
Interaction of complement system and microglia activation in retina and optic nerve in a NMDA damage model.
Kuehn S, Reinehr S, Stute G, Rodust C, Grotegut P, Hensel AT, Burkhard Dick H, Joachim SC
Molecular and cellular neurosciences (2018) : . 234 003 WB; tested species: mouse
Genetically induced brain inflammation by Cnp deletion transiently benefits from microglia depletion.
Garcia-Agudo LF, Janova H, Sendler LE, Arinrad S, Steixner AA, Hassouna I, Balmuth E, Ronnenberg A, Schopf N, van der Flier FJ, Begemann M, et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2019) : fj201900337R. 234 006 ICC, IHC; tested species: mouse
Tmem119-EGFP and Tmem119-CreERT2 transgenic mice for labeling and manipulating microglia.
Kaiser T, Feng G
eNeuro (2019) : . 234 006 IHC; tested species: mouse
Neuroinflammatory Changes in Relation to Cerebrospinal Fluid Viral Load in Simian Immunodeficiency Virus Encephalitis.
Hammoud DA, Sinharay S, Shah S, Schreiber-Stainthorp W, Maric D, Muthusamy S, Lee DE, Lee CA, Basuli F, Reid WC, Wakim P, et al.
mBio (2019) 103: . 234 004 IHC; tested species: monkey
Co-inhibition of PGF and VEGF blocks their expression in mononuclear phagocytes and limits neovascularization and leakage in the murine retina.
Balser C, Wolf A, Herb M, Langmann T
Journal of neuroinflammation (2019) 161: 26. 234 003 IHC; tested species: mouse
Attenuation of epileptogenesis by 2-deoxy-d-glucose is accompanied by increased cerebral glucose supply, microglial activation and reduced astrocytosis.
Leiter I, Bascuñana P, Bengel FM, Bankstahl JP, Bankstahl M
Neurobiology of disease (2019) : 104510. 234 003 IHC; tested species: mouse
Galectin-3 promotes Aβ oligomerization and Aβ toxicity in a mouse model of Alzheimer's disease.
Tao CC, Cheng KM, Ma YL, Hsu WL, Chen YC, Fuh JL, Lee WJ, Chao CC, Lee EHY
Cell death and differentiation (2019) : . 234 004 IHC; tested species: mouse
Inhibition of Bruton's Tyrosine Kinase Modulates Microglial Phagocytosis: Therapeutic Implications for Alzheimer's Disease.
Keaney J, Gasser J, Gillet G, Scholz D, Kadiu I
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology (2019) : . 234 004 IHC; tested species: mouse
CYP46A1 Activation by Efavirenz Leads to Behavioral Improvement without Significant Changes in Amyloid Plaque Load in the Brain of 5XFAD Mice.
Petrov AM, Lam M, Mast N, Moon J, Li Y, Maxfield E, Pikuleva IA
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics (2019) : . 234 006 IHC; tested species: mouse
Neurostatin and other O-acetylated gangliosides show anti-neuroinflammatory activity involving the NFκB pathway.
Yanguas-Casás N, Ojalvo-Sanz AC, Martínez-Vázquez A, Goneau MF, Gilbert M, Nieto-Sampedro M, Romero-Ramírez L
Toxicology and applied pharmacology (2019) : 114627. 234 004 IHC; tested species: mouse
Genetically induced brain inflammation by Cnp deletion transiently benefits from microglia depletion.
Garcia-Agudo LF, Janova H, Sendler LE, Arinrad S, Steixner AA, Hassouna I, Balmuth E, Ronnenberg A, Schopf N, van der Flier FJ, Begemann M, et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2019) : fj201900337R. 234 006 ICC, IHC; tested species: mouse
p75NTR regulates brain mononuclear cell function and neuronal structure in Toxoplasma infection-induced neuroinflammation.
Düsedau HP, Kleveman J, Figueiredo CA, Biswas A, Steffen J, Kliche S, Haak S, Zagrebelsky M, Korte M, Dunay IR
Glia (2019) 671: 193-211. 234 003 IHC; tested species: mouse
The cystine-glutamate exchanger (xCT, Slc7a11) is expressed in significant concentrations in a subpopulation of astrocytes in the mouse brain.
Ottestad-Hansen S, Hu QX, Follin-Arbelet VV, Bentea E, Sato H, Massie A, Zhou Y, Danbolt NC
Glia (2018) 665: 951-970. 234 006 IHC; tested species: mouse
Genetic deletion of xCT attenuates peripheral and central inflammation and mitigates LPS-induced sickness and depressive-like behavior in mice.
Albertini G, Deneyer L, Ottestad-Hansen S, Zhou Y, Ates G, Walrave L, Demuyser T, Bentea E, Sato H, De Bundel D, Danbolt NC, et al.
Glia (2018) 669: 1845-1861. 234 006 IHC; tested species: mouse
p53 in AgRP neurons is required for protection against diet-induced obesity via JNK1.
Quiñones M, Al-Massadi O, Folgueira C, Bremser S, Gallego R, Torres-Leal L, Haddad-Tóvolli R, García-Caceres C, Hernandez-Bautista R, Lam BYH, Beiroa D, et al.
Nature communications (2018) 91: 3432. 234 003 IHC; tested species: mouse
Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies.
Dejanovic B, Huntley MA, De Mazière A, Meilandt WJ, Wu T, Srinivasan K, Jiang Z, Gandham V, Friedman BA, Ngu H, Foreman O, et al.
Neuron (2018) : . 234 004 IHC; tested species: mouse
Glycoprotein NMB: a novel Alzheimer's disease associated marker expressed in a subset of activated microglia.
Hüttenrauch M, Ogorek I, Klafki H, Otto M, Stadelmann C, Weggen S, Wiltfang J, Wirths O
Acta neuropathologica communications (2018) 61: 108. 234 004 IHC; tested species: mouse
A systems-level framework for drug discovery identifies Csf1R as an anti-epileptic drug target.
Srivastava PK, Eyll JV, Godard P, Mazzuferi M, Delahaye-Duriez A, Steenwinckel JV, Gressens P, Danis B, Vandenplas C, Foerch P, Leclercq K, et al.
Nature communications (2018) 91: 3561. 234 004 IHC; tested species: mouse
Long-lasting pathological consequences of overexpression-induced α-synuclein spreading in the rat brain.
Rusconi R, Ulusoy A, Aboutalebi H, Di Monte DA
Aging cell (2018) 172: . 234 004 IHC; tested species: rat
Long-Term Neuroinflammation Induced by Influenza A Virus Infection and the Impact on Hippocampal Neuron Morphology and Function.
Hosseini S, Wilk E, Michaelsen-Preusse K, Gerhauser I, Baumgärtner W, Geffers R, Schughart K, Korte M
The Journal of neuroscience : the official journal of the Society for Neuroscience (2018) 3812: 3060-3080. 234 003 IHC; tested species: mouse
Beneficial effects of n-3 polyunsaturated fatty acids administration in a partial lesion model of Parkinson's disease: The role of glia and NRf2 regulation.
Hernando S, Requejo C, Herran E, Ruiz-Ortega JA, Morera-Herreras T, Lafuente JV, Ugedo L, Gainza E, Pedraz JL, Igartua M, Hernández RM, et al.
Neurobiology of disease (2018) : . 234 003 IHC; tested species: rat
Chronic near lifetime toluene exposure in rodents does not replicate solvent abuse leukoencephalopathy in humans.
Ranson MA, Del Bigio MR
Neurotoxicology (2018) : . 234 003 IHC; tested species: rat
Distinct in vivo roles of secreted APP ectodomain variants APPsα and APPsβ in regulation of spine density, synaptic plasticity, and cognition.
Richter MC, Ludewig S, Winschel A, Abel T, Bold C, Salzburger LR, Klein S, Han K, Weyer SW, Fritz AK, Laube B, et al.
The EMBO journal (2018) : . 234 003 WB, IHC; tested species: mouse
Deficiency of leptin receptor in myeloid cells disrupts hypothalamic metabolic circuits and causes body weight increase.
Gao Y, Vidal-Itriago A, Milanova I, Korpel NL, Kalsbeek MJ, Tom RZ, Kalsbeek A, Hofmann SM, Yi CX
Molecular metabolism (2018) 7: 155-160. 234 003 IHC; tested species: mouse
Microglial Ramification, Surveillance, and Interleukin-1β Release Are Regulated by the Two-Pore Domain K+Channel THIK-1.
Madry C, Kyrargyri V, Arancibia-Cárcamo IL, Jolivet R, Kohsaka S, Bryan RM, Attwell D
Neuron (2018) 972: 299-312.e6. 234 003 IHC; tested species: mouse
Widespread transduction of astrocytes and neurons in the mouse central nervous system after systemic delivery of a self-complementary AAV-PHP.B vector.
Rincon MY, de Vin F, Duqué SI, Fripont S, Castaldo SA, Bouhuijzen-Wenger J, Holt MG
Gene therapy (2018) : . 234 003 IHC; tested species: mouse
Effects of the ecto-ATPase apyrase on microglial ramification and surveillance reflect cell depolarization, not ATP depletion.
Madry C, Arancibia-Cárcamo IL, Kyrargyri V, Chan VTT, Hamilton NB, Attwell D
Proceedings of the National Academy of Sciences of the United States of America (2018) 1157: E1608-E1617. 234 003 IHC; tested species: rat
Optic tract injury after closed head traumatic brain injury in mice: A model of indirect traumatic optic neuropathy.
Evanson NK, Guilhaume-Correa F, Herman JP, Goodman MD
PloS one (2018) 135: e0197346. 234 003 IHC; tested species: mouse
Dietary sugars, not lipids, drive hypothalamic inflammation.
Gao Y, Bielohuby M, Fleming T, Grabner GF, Foppen E, Bernhard W, Guzmán-Ruiz M, Layritz C, Legutko B, Zinser E, García-Cáceres C, et al.
Molecular metabolism (2017) 68: 897-908. 234 003 IHC
Delayed histochemical alterations within the neurovascular unit due to transient focal cerebral ischemia and experimental treatment with neurotrophic factors.
Michalski D, Pitsch R, Pillai DR, Mages B, Aleithe S, Grosche J, Martens H, Schlachetzki F, Härtig W
PloS one (2017) 124: e0174996. 234 003 IHC
TNFα drives mitochondrial stress in POMC neurons in obesity.
Yi CX, Walter M, Gao Y, Pitra S, Legutko B, Kälin S, Layritz C, García-Cáceres C, Bielohuby M, Bidlingmaier M, Woods SC, et al.
Nature communications (2017) 8: 15143. 234 003 IHC; tested species: mouse
Neurovascular Specifications in the Alzheimer-Like Brain of Mice Affected by Focal Cerebral Ischemia: Implications for Future Therapies.
Michalski D, Hofmann S, Pitsch R, Grosche J, Härtig W
Journal of Alzheimer's disease : JAD (2017) 592: 655-674. 234 003 IHC; tested species: mouse
Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity.
Quarta C, Clemmensen C, Zhu Z, Yang B, Joseph SS, Lutter D, Yi CX, Graf E, García-Cáceres C, Legutko B, Fischer K, et al.
Cell metabolism (2017) 264: 620-632.e6. 234 003 IHC; tested species: mouse
Damaged Neocortical Perineuronal Nets Due to Experimental Focal Cerebral Ischemia in Mice, Rats and Sheep.
Härtig W, Mages B, Aleithe S, Nitzsche B, Altmann S, Barthel H, Krueger M, Michalski D
Frontiers in integrative neuroscience (2017) 11: 15. 234 004 IHC; tested species: mouse,rat,sheep
Neuroprotection and Blood-Brain Barrier Restoration by Salubrinal After a Cortical Stab Injury.
Barreda-Manso MA, Yanguas-Casás N, Nieto-Sampedro M, Romero-Ramírez L
Journal of cellular physiology (2017) 2326: 1501-1510. 234 004 IHC; tested species: mouse
Ablation of peri-insult generated granule cells after epilepsy onset halts disease progression.
Hosford BE, Rowley S, Liska JP, Danzer SC
Scientific reports (2017) 71: 18015. 234 003 IHC; tested species: rat
Type I Interferon response in olfactory bulb, the site of tick-borne flavivirus accumulation, is primarily regulated by IPS-1.
Kurhade C, Zegenhagen L, Weber E, Nair S, Michaelsen-Preusse K, Spanier J, Gekara NO, Kröger A, Överby AK
Journal of neuroinflammation (2016) 13: 22. 234 003 IHC
Impact of rapamycin on status epilepticus induced hippocampal pathology and weight gain.
Hester MS, Hosford BE, Santos VR, Singh SP, Rolle IJ, LaSarge CL, Liska JP, Garcia-Cairasco N, Danzer SC
Experimental neurology (2016) 280: 1-12. 234 003 IHC; tested species: mouse
Ablation of Newly Generated Hippocampal Granule Cells Has Disease-Modifying Effects in Epilepsy.
Hosford BE, Liska JP, Danzer SC
The Journal of neuroscience : the official journal of the Society for Neuroscience (2016) 3643: 11013-11023. 234 003 IHC; tested species: mouse
Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid.
Schläger C, Körner H, Krueger M, Vidoli S, Haberl M, Mielke D, Brylla E, Issekutz T, Cabañas C, Nelson PJ, Ziemssen T, et al.
Nature (2016) 5307590: 349-53. 234 004 IHC
Low Density Lipoprotein-Receptor Related Protein 1 Is Differentially Expressed by Neuronal and Glial Populations in the Developing and Mature Mouse Central Nervous System.
Auderset L, Cullen CL, Young KM
PloS one (2016) 116: e0155878. 234 004 IHC
L-type Calcium Channel Cav1.2 Is Required for Maintenance of Auditory Brainstem Nuclei.
Ebbers L, Satheesh SV, Janz K, Rüttiger L, Blosa M, Hofmann F, Morawski M, Griesemer D, Knipper M, Friauf E, Nothwang HG, et al.
The Journal of biological chemistry (2015) 29039: 23692-710. 234 003 IHC
Cellular distribution of the NMDA-receptor activated synapto-nuclear messenger Jacob in the rat brain.
Mikhaylova M, Karpova A, Bär J, Bethge P, YuanXiang P, Chen Y, Zuschratter W, Behnisch T, Kreutz MR
Brain structure & function (2014) 2193: 843-60. 234 004 IHC
Capillary pericytes regulate cerebral blood flow in health and disease.
Hall CN, Reynell C, Gesslein B, Hamilton NB, Mishra A, Sutherland BA, O'Farrell FM, Buchan AM, Lauritzen M, Attwell D
Nature (2014) 5087494: 55-60. 234 003 IHC; tested species: mouse
Interferon regulatory factor-1 protects from fatal neurotropic infection with vesicular stomatitis virus by specific inhibition of viral replication in neurons.
Nair S, Michaelsen-Preusse K, Finsterbusch K, Stegemann-Koniszewski S, Bruder D, Grashoff M, Korte M, Köster M, Kalinke U, Hauser H, Kröger A, et al.
PLoS pathogens (2014) 103: e1003999. 234 003 IHC; tested species: mouse
A highly secreted sulphamidase engineered to cross the blood-brain barrier corrects brain lesions of mice with mucopolysaccharidoses type IIIA.
Sorrentino NC, D'Orsi L, Sambri I, Nusco E, Monaco C, Spampanato C, Polishchuk E, Saccone P, De Leonibus E, Ballabio A, Fraldi A, et al.
EMBO molecular medicine (2013) 55: 675-90. 234 003 IHC; tested species: mouse
No improvement after chronic ibuprofen treatment in the 5XFAD mouse model of Alzheimer's disease.
Hillmann A, Hahn S, Schilling S, Hoffmann T, Demuth HU, Bulic B, Schneider-Axmann T, Bayer TA, Weggen S, Wirths O
Neurobiology of aging (2012) 334: 833.e39-50. 234 003 IHC; tested species: mouse
Coping with AIDS: issues of accountability in the dental office.
Cutler LS
Journal - Connecticut State Dental Association (1988) 621: 20-2. 234 003 IHC; tested species: mouse
Blood-Brain Barrier Leakage during Early Epileptogenesis Is Associated with Rapid Remodeling of the Neurovascular Unit.
Bankstahl M, Breuer H, Leiter I, Märkel M, Bascuñana P, Michalski D, Bengel FM, Löscher W, Meier M, Bankstahl JP, Härtig W, et al.
eNeuro () 53: . 234 003 IHC; tested species: rat
Memantine treatment of juvenile rats with kaolin-induced hydrocephalus.
Di Curzio DL, Nagra G, Mao X, Del Bigio MR
Brain research (2018) 1689: 54-62. 234 003 IHC-P; tested species: rat
The metalloprotease ADAMTS4 generates N-truncated Aβ4-x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer's disease.
Walter S, Jumpertz T, Hüttenrauch M, Ogorek I, Gerber H, Storck SE, Zampar S, Dimitrov M, Lehmann S, Lepka K, Berndt C, et al.
Acta neuropathologica (2018) : . 234 004 IHC-P; tested species: mouse
Synaptic Systems Gesellschaft für neurobiologische Forschung, Entwicklung und Produktion mbH | Rudolf-Wissell-Str. 28 | 37079 Goettingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: http://www.sysy.com | E-Mail: sales@sysy.com | Impressum - Legal Note | Privacy Policy
Design by BLACKBIT interactive GmbH

Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: http://www.sysy.com | E-Mail: sales@sysy.com