Cat. No.: 150 103
Amount: 50 µg
Price:
$455.00
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| Cat. No. 150 103 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications |
IP: not tested yet ICC: not tested yet IHC: not tested yet IHC-P: not tested yet |
| Immunogen | Recombinant protein corresponding to AA 318 to 415 from rat CASK (UniProt Id: Q62915) |
| Reactivity |
Reacts with: rat (Q62915), mouse (O70589). Other species not tested yet. |
| Data sheet | 150_103.pdf |
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CASK, like PSD 95, belongs to the family of membrane associated guanylate kinase homologues (MAGUKs) but contains an additional N-terminal CaM kinase-like domain.
It has been shown to interact with Mint and Veli via its N-terminal domains. PDZ domains are present in all three proteins of the complex. They are free to recruit other proteins like neurexins and syndecans. The complex of CASK, Velis and Mint is conserved across kingdoms and has also been observed in C. elegans.