Tailor-made Antibodies
and Tools for Life Science
Home|||||Technical Support

GABABR2 antibody - 322 203

GABABR2 is a metabotropic GABA receptor
Rabbit polyclonal purified antibody
Cat. No.: 322 203
Amount: 50 µg
Price: $375.00
Cat. No. 322 203 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: 1 : 500 gallery  
IHC: 1 : 200 up to 1 : 500 gallery  
IHC-P: not tested yet
Immunogen Synthetic peptide corresponding to AA 917 to 940 from rat GABABR2 (UniProt Id: O88871)
Reactivity Reacts with: rat (O88871), mouse (Q80T41).
Other species not tested yet.
Data sheet 322_203.pdf

References for GABABR2 - 322 203

Complex formation of APP with GABAB receptors links axonal trafficking to amyloidogenic processing.
Dinamarca MC, Raveh A, Schneider A, Fritzius T, Früh S, Rem PD, Stawarski M, Lalanne T, Turecek R, Choo M, Besseyrias V, et al.
Nature communications (2019) 101: 1331. 322 203 IP; tested species: mouse
Cat. No.: 322 203
Amount: 50 µg
Price: $375.00
Complex formation of APP with GABAB receptors links axonal trafficking to amyloidogenic processing.
Dinamarca MC, Raveh A, Schneider A, Fritzius T, Früh S, Rem PD, Stawarski M, Lalanne T, Turecek R, Choo M, Besseyrias V, et al.
Nature communications (2019) 101: 1331. 322 203 IP; tested species: mouse
Background

Metabotropic g-aminobutyric acid type B receptors (GABABRs) are involved in the modulation of synaptic transmission and activity of cerebellar and thalamic neurons.
In contrast to the ionotrophic GABA-A receptors they are linked to G-proteins underlying the slow inhibitory postsynaptic potentials.
GABABR 1 and GABABR 2 have been shown to form heterodimers.