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GluA2 antibody - 182 211

GluAs are ionotropic glutamate receptors involved in rapid excitatory neurotransmission
Mouse monoclonal purified IgM
Cat. No.: 182 211
Amount: 100 µg
Price: $415.00
Cat. No. 182 211 100 µg purified IgM, lyophilized. Azide was added before lyophilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 up to 1 : 10000 (AP staining) gallery  
IP: not tested yet
ICC: not tested yet
IHC: not tested yet
IHC-P: not tested yet
Clone 143A10
Subtype IgM
Immunogen Recombinant protein corresponding to AA 836 to 883 from rat GluA2 (UniProt Id: P19491)
Reactivity Reacts with: rat (P19491), mouse (P23819).
Other species not tested yet.
Matching control protein/peptide 182-1P
Data sheet 182_211.pdf

References for GluA2 - 182 211

Profiling of purified autophagic vesicle degradome in the maturing and aging brain.
Kallergi E, Siva Sankar D, Matera A, Kolaxi A, Paolicelli RC, Dengjel J, Nikoletopoulou V
Neuron (2023) : . 182 211 WB; tested species: mouse
Dendritic autophagy degrades postsynaptic proteins and is required for long-term synaptic depression in mice.
Kallergi E, Daskalaki AD, Kolaxi A, Camus C, Ioannou E, Mercaldo V, Haberkant P, Stein F, Sidiropoulou K, Dalezios Y, Savitski MM, et al.
Nature communications (2022) 131: 680. 182 211 WB; tested species: mouse
Cat. No.: 182 211
Amount: 100 µg
Price: $415.00
Profiling of purified autophagic vesicle degradome in the maturing and aging brain.
Kallergi E, Siva Sankar D, Matera A, Kolaxi A, Paolicelli RC, Dengjel J, Nikoletopoulou V
Neuron (2023) : . 182 211 WB; tested species: mouse
Dendritic autophagy degrades postsynaptic proteins and is required for long-term synaptic depression in mice.
Kallergi E, Daskalaki AD, Kolaxi A, Camus C, Ioannou E, Mercaldo V, Haberkant P, Stein F, Sidiropoulou K, Dalezios Y, Savitski MM, et al.
Nature communications (2022) 131: 680. 182 211 WB; tested species: mouse
Background

Ionotropic glutamate receptors (iGluRs) mediate rapid excitatory neurotransmission in the mammalian CNS. They can be subdivided into three major groups, the AMPA/GluA, NMDA/GluN and kainate/GluK receptors (KARs). mRNAs coding for glutamate receptors are substrates for an adenosine deaminase acting on RNA (ADAR) that increases the diversity of these proteins.
Glutamate receptors of the AMPA subtype are monovalent cation channels and are composed of the four AMPA subunits GluA 1, GluA 2, GluA 3, and GluA 4.