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Available Products General Information References

Protein A Agarose

Protein A resin for IgG purification

General Information

As the developer of high quality antibodies, we have extended our product portfolio by Protein A Agarose affinity resins.
Protein A is a cell wall protein from Staphylococcus aureus and is commonly used for the affinity purification or pull downs of IgG class antibodies. It binds to immunoglobulins through interaction with the IgG heavy chain within the Fc region. Antibodies from serum (polyclonal antibodies), ascites or cell culture supernatant of hybridoma cell lines (monoclonal antibodies) can thus be easily isolated.

 

Protein A does not bind to all IgG classes from all species equivalently well.

 

Species

Subclass

Protein A
binding

Human

IgA

variable

IgD

-

IgE

-

IgG1

++++

IgG2

++++

IgG3

-

IgG4

++++

IgM

variable

Avian egg yolk

IgY

-

Cow

IgG

++

Dog

IgG

++

Goat

IgG

-

Guinea pig

IgG1

++++

IgG2

++++

Hamster

IgG

+

Horse

IgG

++

Llama

IgG

-

Monkey (rhesus)

IgG

++++

Mouse

IgG1

+

IgG2a

++++

IgG2b

+++

IgG3

++

IgM

-

Pig

IgG

+++

Rabbit

IgG1

++++

Rat

IgG1

-

IgG2a

-

IgG2b

-

IgG3

+

Sheep

IgG

+/-

 

Synaptic Systems Gesellschaft für neurobiologische Forschung, Entwicklung und Produktion mbH | Rudolf-Wissell-Str. 28 | 37079 Goettingen | Germany
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Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: http://www.sysy.com | E-Mail: sales@sysy.com