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PSD95 sdAb - FluoTag-X2 - N3702-SC5-L

PSD 95 is a component of postsynaptic densities in central synapses

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FluoTags are camelid single domain antibodies consisting only of one antigen binding site of a Alpaka heavy chain antibody. With only ~15 kDa, these Tags are about 10-times smaller than conventional IgG antibody molecules.

Camelid single domain antibody

Cat. No.: N3702-SC5-L
Amount: 200 µl
Price: $485.00
Cat. No. N3702-SC5-L

2.5 µM fluorescently labeled sdAb in buffered saline, 50% glycerol, 0.09% sodium azide

Storage –80°C for up to 12 month
Applications WB: N/A
IP: not tested yet
ICC: 1 : 500
IHC: 1 : 200 up to 1 : 500
IHC-P/FFPE: not tested yet
Label Sulfo-Cyanine 5, two fluorophores coupled to one FluoTag
Clone 1B2
Subtype single domain
Immunogen Recombinant protein corresponding to AA 68 to 251 from mouse PSD95 (UniProt Id: Q62108)
Reactivity Reacts with: mouse (Q62108), rat (P31016).
Other species not tested yet.
Specificity Specific for PSD 95
Matching control protein/peptide 124-01P
Documents data sheet

Cat. No.: N3702-SC5-L
Quantity: 200 µl
Price: $485.00
Background

PSD95 (postsynaptic density protein 95 kDa, also called SAP 90: synapse associated protein of 90 kDa and DLG 4) is a component of postsynaptic densities in central synapses. It contains three PDZ domains. The first and second PDZ domain localizes NMDA receptors and K+ channels to synapses, the third binds to neuroligins which are neuronal cell adhesion molecules that interact with β-neurexins and form intercellular junctions. Thus different PDZ domains of PSD 95 might be specialized for distinct functions.