Zyxin
A protein involved in the regulation of actin dynamics
References SySy zyxin antibodies
Delaroche D, Cantrelle FX, Subra F, Van Heijenoort C, Guittet E, Jiao CY, Blanchoin L, Chassaing G, Lavielle S, Auclair C & Sagan S (2010). Cell-penetrating peptides with intracellular actin-remodeling activity in malignant fibroblasts. Journal of Biological Chemistry 285: 7712-21.
ICC
Low SH, Mukhina S, Srinivas V, Ng CZ & Murata-Hori M (2010). Domain analysis of alpha-actinin reveals new aspects of its association with F-actin during cytokinesis. Experimental Cell Research 316: 1925-34.
ICC in supplement
Vollenbröker B, George B, Wolfgart M, Saleem MA, Pavenstädt H & Weide T (2009). mTOR regulates expression of slit diaphragm proteins and cytoskeleton structure in podocytes. American Journal of Physiology. Renal Physiology 296: 418-26.
WB, ICC
Vervenne HB, Crombez KR, Delvaux EL, Janssens V, Van de Ven WJ & Petit MM (2009). Targeted disruption of the mouse Lipoma Preferred Partner gene. Biochemical and Biophysical Research Communications 379: 368-73.
WB
Mori M, Nakagami H, Koibuchi N, Miura K, Takami Y, Koriyama H, Hayashi H, Sabe H, Mochizuki N, Morishita R & Kaneda Y (2009). Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis. Molecular Biology of the Cell 20: 3115-24.
WB, ICC
Guo WH & Wang YL (2007). Retrograde fluxes of focal adhesion proteins in response to cell migration and mechanical signals. Molecular Biology of the Cell 18: 4519-27.
ICC
Coutts AS, MacKenzie E, Griffith E & Black DM (2003). TES is a novel focal adhesion protein with a role in cell spreading. Journal of Cell Science 116: 897-906.
WB, ICC
Garvalov BK, Higgins TE, Sutherland JD, Zettl M, Scaplehorn N, Kocher T, Piddini E, Griffiths G, Way M (2003). The conformational state of Tes regulates its zyxin-dependent recruitment to focal adhesions. Journal of Cell Biology 161: 33-9.
WB, ICC
Rottner K, Krause M, Gimona M, Small JV, Wehland J (2001). Zyxin is not colocalized with vasodilator - stimulated phosphoprotein (VASP) at lamellipodial tips and exhibits different dynamics to vinculin, paxillin, and VASP in focal adhesions. Molecular Biology of the Cell. 12: 3103-13.
Description of Clone 164D4; WB, ICC
General references zyxin
Schick B, Praetorius M, Eigenthaler M, Mack A, Plinkert P, Walter U, Dazert S, Knipper M (2003). Expression of VASP and zyxin in cochlear pillar cells: indication for actin-based dynamics? Cell and Tissue Research 311: 315-23.
van der Gaag EJ, Leccia MT, Dekker SK, Jalbert NL, Amodeo DM, Byers HR (2002). Role of zyxin in differential cell spreading and proliferation of melanoma cells and melanocytes. Journal of Investigative Dermatology 118: 246-54.
Fradelizi J, Noireaux V, Plastino J, Menichi B, Louvard D, Sykes C, Golsteyn RM, Friederich E (2001). ActA and human zyxin harbour Arp2/3-independent actin-polymerization activity. Nature Cell Biology 3: 699-707.
Li B & Trueb B (2001). Analysis of the alpha-actinin/zyxin interaction. Journal of Biological Chemistry 276: 33328-35.
Nix DA, Fradelizi J, Bockholt S, Menichi B, Louvard D, Friederich E, Beckerle MC (2001). Targeting of zyxin to sites of actin membrane interaction and to the nucleus. Journal of Biological Chemistry 276: 34759-67.
Hirota T, Morisaki T, Nishiyama Y, Marumoto T, Tada K, Hara T, Masuko N, Inagaki M, Hatakeyama K, Saya H (2000). Zyxin, a regulator of actin filament assembly, targets the mitotic apparatus by interacting with h-warts/LATS1 tumor suppressor. Journal of Cell Biology 149: 1073-86.