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SY SY - Synaptic Systems SY SY - Synaptic Systems

ZnT 3

A synaptic vesicle located zinc-transporter

References SySy ZnT 3 antibodies

Grønborg M, Pavlos NJ, Brunk I, Chua JJ, Münster-Wandowski A, Riedel D, Ahnert-Hilger G, Urlaub H & Jahn R (2010). Quantitative comparison of glutamatergic and GABAergic synaptic vesicles unveils selectivity for few proteins including MAL2, a novel synaptic vesicle protein. Journal of Neuroscience 30: 2-12. rabbit antiserum; WB

General references ZnT 3

Salazar G, Craige B, Love R, Kalman D & Faundez V (2005). Vglut1 and ZnT3 co-targeting mechanisms regulate vesicular zinc stores in PC12 cells. Journal of Cell Science 118(Pt9): 1911-21.

Salazar G, Love R, Werner E, Doucette MM, Cheng S, Levey A & Faundez V (2004). The zinc transporter ZnT3 interacts with AP-3 and it is preferentially targeted to a distinct synaptic vesicle subpopulation. Molecular Biology of the Cell 15: 575-87.

Lee JY, Cole TB, Palmiter RD & Koh JY (2000). Accumulation of zinc in degenerating hippocampal neurons of ZnT3-null mice after seizures: evidence against synaptic vesicle origin. Journal of Neuroscience 20: RC79. 1-5.

Cole TB, Wenzel HJ, Kafer KE, Schwartzkroin PA & Palmiter RD (1999). Elimination of zinc from synaptic vesicles in the intact mouse brain by disruption of the ZnT3 gene. Proceedings of the National Academy of Sciences USA 96: 1716-21.

Wenzel HJ, Cole TB, Born DE, Schwartzkroin PA & Palmiter RD (1997). TUltrastructural localization of zinc transporter-3 (ZnT-3) to synaptic vesicle membranes within mossy fiber boutons in the hippocampus of mouse and monkey. Proceedings of the National Academy of Sciences USA 94: 12676-81.


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Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: http://www.sysy.com | E-Mail: sales@sysy.com