ZnT 1

An abundantly expressed Zinc-transporter involved in the efflux of Zn²⁺

General references ZnT 1

Ohana E, Sekler I, Kaisman T, Kahn N, Cove J, Silverman WF, Amsterdam A & Hershfinkel M (2006). Silencing of ZnT-1 expression enhances heavy metal influx and toxicity. Journal of Molecular Medicine 84: 753-63.

Lovell MA, Smith JL, Xiong S & Markesbery WR (2005). Alterations in zinc transporter protein-1 (ZnT-1) in the brain of subjects with mild cognitive impairment, early, and late-stage Alzheimer's disease. Neurotoxicity Research 7: 265-71.

Nolte C, Gore A, Sekler I, Kresse W, Hershfinkel M, Hoffmann A, Kettenmann H & Moran A (2004). ZnT-1 expression in astroglial cells protects against zinc toxicity and slows the accumulation of intracellular zinc. Glia 48: 145-55. Erratum in: Glia 48: 346

Ford D (2004). Intestinal and placental zinc transport pathways. Proceedings of the Nutrition Society 63: 21-9. Review

Nitzan YB, Sekler I, Hershfinkel M, Moran A & Silverman WF (2002). Postnatal regulation of ZnT-1 expression in the mouse brain. Brain Research Developmental Brain Research 137: 149-57.

McMahon RJ & Cousins RJ (1998). Regulation of the zinc transporter ZnT-1 by dietary zinc. Proceedings of the National Academy of Sciences USA 95: 4841-6.