Vti1b

A SNARE protein involved in endosomal fusion events

References SySy vti1b antibodies

Qu B, Pattu V, Junker C, Schwarz EC, Bhat SS, Kummerow C, Marshall M, Matti U, Neumann F, Pfreundschuh M, Becherer U, Rieger H, Rettig J & Hoth M (2011). Docking of lytic granules at the immunological synapse in human CTL requires Vti1b-dependent pairing with CD3 endosomes. Journal of Immunology 186: 6894-904. ICC

Offenhäuser C, Lei N, Roy S, Collins BM, Stow JL & Murray RZ (2011). Syntaxin 11 binds Vti1b and regulates late endosome to lysosome fusion in macrophages. Traffic 12: 762-73. WB, IP, ICC

General references vti1b

Murray RZ, Wylie FG, Khromykh T, Hume DA & Stow JL (2005). Syntaxin 6 and Vti1b form a novel SNARE complex, which is up-regulated in activated macrophages to facilitate exocytosis of tumor necrosis Factor-alpha. Journal of Biological Chemistry 280: 10478-83.

Hirst J, Miller SE, Taylor MJ, von Mollard GF & Robinson MS (2004). EpsinR is an adaptor for the SNARE protein Vti1b. Molecular Biology of the Cell 15: 5593-602.

Atlashkin V, Kreykenbohm V, Eskelinen EL, Wenzel D, Fayyazi A & Fischer von Mollard G (2003). Deletion of the SNARE vti1b in mice results in the loss of a single SNARE partner, syntaxin 8. Molecular and Cellular Biology 23: 5198-207.

Antonin W, Dulubova I, Arac D, Pabst S, Plitzner J, Rizo J & Jahn R (2002). The N-terminal domains of syntaxin 7 and vti1b form three-helix bundles that differ in their ability to regulate SNARE complex assembly. Journal of Biological Chemistry 277: 36449-56.

Kreykenbohm V, Wenzel D, Antonin W, Atlachkine V & von Mollard GF (2002). The SNAREs vti1a and vti1b have distinct localization and SNARE complex partners. European Journal of Cell Biology 81: 273-80.