VPS 45

A protein of the SM family, probably involved in trans-Golgi network trafficking

General Information

The vesicular transport protein VPS 45 has first been discovered in yeast, and homologues were later found in mammals. This ubiquitiously expressed protein belongs to the STxBP/Unc-18/Sec1 family. It is probably involved in vesicle-mediated protein trafficking from the Golgi stack through the trans-Golgi network. The highest expression levels are observed in brain and testis.