VGAT (vesicular GABA transporter)

GABA transporter in the membrane of synaptic vesicles

References SySy VGAT antibodies

Martens H, Weston MC, Boulland JL, Grønborg M, Grosche J, Kacza J, Hoffmann A, Matteoli M, Takamori S, Harkany T, Chaudhry FA, Rosenmund C, Erck C, Jahn R & Härtig W (2008). Unique Luminal Localization of VGAT-C Terminus Allows for Selective Labeling of Active Cortical GABAergic Synapses. Journal of Neuroscience 28: 13125-13131. Description of lumenal domain rabbit antibody

Ferguson SM, Brasnjo G, Hayashi M, Wölfel M, Collesi C, Giovedi S, Raimondi A, Gong LW, Ariel P, Paradise S, O'toole E, Flavell R, Cremona O, Miesenböck G, Ryan TA & De Camilli P (2007). A selective activity-dependent requirement for dynamin 1 in synaptic vesicle endocytosis. Science 316: 570-4. WB in supplement

Baer K, Bürli T, Huh KH, Wiesner A, Erb-Vögtli S, Göckeritz-Dujmovic D, Moransard M, Nishimune A, Rees MI, Henley JM, Fritschy JM & Fuhrer C (2007). PICK1 interacts with alpha7 neuronal nicotinic acetylcholine receptors and controls their clustering. Molecular and Cellular Neurosciences 35: 339-55. cytoplasmic domain rabbit antibody and clone 117G4; ICC

Bogen IL, Boulland JL, Mariussen E, Wright MS, Fonnum F, Kao HT & Walaas SI (2006). Absence of synapsin I and II is accompanied by decreases in vesicular transport of specific neurotransmitters. Journal of Neurochemistry 96: 1458-66. Clone 117G4; IHC

Tafoya LC, Mameli M, Miyashita T, Guzowski JF, Valenzuela CF & Wilson MC (2006). Expression and function of SNAP-25 as a universal SNARE component in GABAergic neurons. Journal of Neuroscience 26: 7826-38. cytoplasmic domain rabbit antibody and clone 117G4; WB, ICC, IHC

Pollard KS, Salama SR, Lambert N, Lambot MA, Coppens S, Pedersen JS, Katzman S, King B, Onodera C, Siepel A, Kern AD, Dehay C, Igel H, Ares M Jr, Vanderhaeghen P & Haussler D (2006). An RNA gene expressed during cortical development evolved rapidly in humans. Nature 443: 167-72. cytoplasmic domain rabbit antibody; IHC in human

Hartman KN, Pal SK, Burrone J & Murthy VN (2006). Activity-dependent regulation of inhibitory synaptic transmission in hippocampal neurons. Nature Neuroscience 9: 642-9. cytoplasmic domain rabbit antibody; ICC

Berghuis P, Dobszay MB, Wang X, Spano S, Ledda F, Sousa KM, Schulte G, Ernfors P, Mackie K, Paratcha G, Hurd YL & Harkany T (2005). Endocannabinoids regulate interneuron migration and morphogenesis by transactivating the TrkB receptor. Proceedings of the National Academy of Sciences USA 102: 19115-20. cytoplasmic domain rabbit antibody; ICC

Saito T, Iwata N, Tsubuki S, Takaki Y, Takano J, Huang SM, Suemoto T, Higuchi M & Saido TC (2005). Somatostatin regulates brain amyloid beta peptide Abeta42 through modulation of proteolytic degradation. Nature Medicine 11: 434-9. Clone 117G4; IHC

Prange O, Wong TP, Gerrow K, Wang YT & El-Husseini A. (2004). A balance between excitatory and inhibitory synapses is controlled by PSD-95 and neuroligin. Proceedings of the National Academy of Sciences USA 101: 13915-20. cytoplasmic domain rabbit antibody; ICC

Geigerseder C, Doepner RF, Thalhammer A, Krieger A & Mayerhofer A (2004). Stimulation of TM3 Leydig cell proliferation via GABA(A) receptors: a new role for testicular GABA. Reproductive Biology and Endocrinology 2: 13. cytoplasmic domain rabbit antibody; IHC

Wojcik SM, Rhee JS, Herzog E, Sigler A, Jahn R, Takamori S, Brose N & Rosenmund C (2004). An essential role for vesicular glutamate transporter1 (VGLUT1) in postnatal development and control of quantal size. Proceedings of the National Academy of Sciences USA 101: 7158-63. cytoplasmic domain rabbit antibody; WB

Hartig W, Riedel A, Grosche J, Edwards RH, Fremeau RT Jr, Harkany T, Brauer K & Arendt T (2003). Complementary distribution of vesicular glutamate transporters 1 and 2 in the nucleus accumbens of rat: Relationship to calretinin-containing extrinsic innervation and calbindin-immunoreactive neurons. Journal of Comparative Neurologie 465: 1-10. cytoplasmic domain rabbit antibody; IHC

Geigerseder C, Doepner R, Thalhammer A, Frungieri MB, Gamel-Didelon K, Calandra RS, Kohn FM & Mayerhofer A (2003). Evidence for a GABAergic system in rodent and human testis: local GABA production and GABA receptors. Neuroendocrinology 77: 314-23. cytoplasmic domain rabbit antibody; IHC

Takamori S, Riedel D & Jahn R (2000). Immunoisolation of GABA-specific synaptic vesicles defines a functionally distinct subset of synaptic vesicles. Journal of Neuroscience 20: 4904-11. Description of cytoplasmic domain rabbit antibody

General references VGAT

Chaudhry FA, Reimer RJ, Bellocio E, Danbolt NC, Osen KK, Edwards RH & Storm-Mathisen J (1998). The vesicular GABA transporter, VGAT, localizes to synaptic vesicles in sets of glycinergic as well as GABAergic neurons. Journal of Neuroscience 18: 9733-50.

McIntire SL, Reimer RJ, Schuske K, Edwards RH & Jorgensen EM (1997). Identification and characterization of the vesicular GABA transporter. Nature 389: 870-6.

Sagne C, El Mestikawy S, Isambert M-F, Hamon M, Henry J-P, Giros B & Gasnier B (1997). Cloning of a functional vesicular GABA and glycine transporter by screening of genome databases. FEBS Letter 417: 177-83.

Hell JW, Maycox PR, Stadler H & Jahn R (1988). Uptake of GABA by rat brain synaptic vesicles isolated by a new procedure. EMBO Journal 7: 3023-9.