VAMP 4

A v-SNARE involved in the maturation of secretory granules

References SySy VAMP 4 antibodies

Laufman O, Hong W & Lev S (2011). The COG complex interacts directly with Syntaxin 6 and positively regulates endosome-to-TGN retrograde transport. Journal of Cell Biology 194: 459-72. WB, ICC

Pérez-Victoria FJ & Bonifacino JS (2009). Dual roles of the mammalian GARP complex in tethering and SNARE complex assembly at the trans-golgi network. Moleculad and Cellular Biology 29: 5251-63. WB

Cocucci E, Racchetti G, Rupnik M & Meldolesi J (2008). The regulated exocytosis of enlargeosomes is mediated by a SNARE machinery that includes VAMP4. Journal of Cell Science 121(Pt18): 2983-91. WB, ICC

Takamori S, Holt M, Stenius K, Lemke EA, Grønborg M, Riedel D, Urlaub H, Schenck S, Brügger B, Ringler P, Müller SA, Rammner B, Gräter F, Hub JS, De Groot BL, Mieskes G, Moriyama Y, Klingauf J, Grubmüller H, Heuser J, Wieland F & Jahn R (2006). Molecular anatomy of a trafficking organelle. Cell 127: 831-46. WB in supplement

Dresbach T, Torres V, Wittenmayer N, Altrock WD, Zamorano P, Zuschratter W, Nawrotzki R, Ziv NE, Garner CC & Gundelfinger ED (2006). Assembly of active zone precursor vesicles: obligatory trafficking of presynaptic cytomatrix proteins Bassoon and Piccolo via a trans-Golgi compartment. Journal of Biological Chemistry 281: 6038-47. ICC

Nakamura N, Fukuda H, Kato A & Hirose S (2005). MARCH-II is a syntaxin-6-binding protein involved in endosomal trafficking. Molecular Biology of the Cell 16: 1696-710. WB

Vetrivel KS, Cheng H, Lin W, Sakurai T, Li T, Nukina N, Wong PC, Xu H & Thinakaran G (2004). Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes. Journal of Biological Chemistry 279: 44945-54. WB

General references VAMP 4

Mallard F, Tang BL, Galli T, Tenza D, Saint-Pol A, Yue X, Antony C & Hong W (2002). Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform. Journal of Cell Biology 156: 653-64.

Peden AA, Park GY & Scheller RH (2001). The Di-leucine motif of vesicle-associated membrane protein 4 is required for its localization and AP-1 binding. Journal of Biological Chemistry 276: 49183-7.

Steegmaier M, Klumperman J, Foletti DL, Yoo JS & Scheller RH (1999). Vesicle-associated membrane protein 4 is implicated in trans-Golgi network vesicle trafficking. Molecular Biology of the Cell 10: 1957-72.