VAChT (vesicular acetylcholine transporter)
Acetylcholine transporter in the membrane of synaptic vesicles
References SySy VAChT antibodies
Nikolajsen GN, Jensen MS & West MJ (2011). Cholinergic axon length reduced by 300 meters in the brain of an Alzheimer mouse model. Neurobiology of Aging 32: 1927-31. rabbit antibody; IHCCea-del Rio CA, Lawrence JJ, Tricoire L, Erdelyi F, Szabo G & McBain CJ (2010). M3 muscarinic acetylcholine receptor expression confers differential cholinergic modulation to neurochemically distinct hippocampal basket cell subtypes. Journal of Neuroscience 30: 6011-24. rabbit antibody; IHC
Madhusudan A, Sidler C & Knuesel I (2009). Accumulation of reelin-positive plaques is accompanied by a decline in basal forebrain projection neurons during normal aging. European Journal of Neuroscience 30: 1064-76. rabbit antibody; IHC
de Castro BM, De Jaeger X, Martins-Silva C, Lima RD, Amaral E, Menezes C, Lima P, Neves CM, Pires RG, Gould TW, Welch I, Kushmerick C, Guatimosim C, Izquierdo I, Cammarota M, Rylett RJ, Gomez MV, Caron MG, Oppenheim RW, Prado MA & Prado VF (2009). The vesicular acetylcholine transporter is required for neuromuscular development and function. Molecular and Cellular Biology 29: 5238-50. rabbit antibody; WB
Wang B, Yang L, Wang Z & Zheng H (2007). Amyolid precursor protein mediates presynaptic localization and activity of the high-affinity choline transporter. Proceedings of the National Academy of Sciences USA 104: 14140-5. rabbit antibody; IHC
Hartig W, Stieler J, Boerema AS, Wolf J, Schmidt U, Weissfuss J, Bullmann T, Strijkstra AM & Arendt T (2007). Hibernation model of tau phosphorylation in hamsters: selective vulnerability of cholinergic basal forebrain neurons - implications for Alzheimer's disease. European Journal of Neuroscience 25: 69-80. rabbit antibody; IHC
Rassadi S, Krishnaswamy A, Pié B, McConnell R, Jacob MH & Cooper E (2005). A null mutation for the α3 nicotinic acetylcholine (ACh) receptor gene abolishes fast synaptic activity in sympathetic ganglia and reveals that ACh output from developing preganglionic terminals is regulated in an activity-dependent retrograde manner. Journal of Neuroscience 25: 8555-66. rabbit antibody; ICC
Morciano M, Burré J, Corvey C, Karras M, Zimmermann H & Volknandt W (2005). Immunoisolation of two synaptic vesicle pools from synaptosomes: a proteomic analysis. Journal of Neurochemistry 95: 1732-45.
General references VAChT
Roghani A & Carroll PT (2002). Analysis of uptake and release of newly synthesized acetylcholine in PC12 cells overexpressing the rat vesicular acetylcholine transporter (VAChT). Brain Research Molecular Brain Research 100: 21-30.Dolezal V, Castell X, Tomasi M & Diebler MF (2001). Stimuli that induce a cholinergic neuronal phenotype of NG108-15 cells upregulate ChAT and VAChT mRNAs but fail to increase VAChT protein. Brain Research Bulletin 54: 363-73.
Mallet J, Houhou L, Pajak F, Oda Y, Cervini R, Bejanin S & Berrard S (1998). The cholinergic locus: ChAT and VAChT genes. Journal of Physiology Paris 92: 145-7. Review
Li JY, Dahlstrom AM, Hersh LB & Dahlstrom A (1998). Fast axonal transport of the vesicular acetylcholine transporter (VAChT) in cholinergic neurons in the rat sciatic nerve. Neurochemistry International 32: 457-67.
Tao-Cheng JH & Eiden LE (1998). The vesicular monoamine transporter VMAT2 and vesicular acetylcholine transporter VAChT are sorted to separate vesicle populations in PC12 cells. Advances in Pharmacology 42: 250-3. No abstract available
Arvidsson U, Riedl M, Elde R & Meister B (1997). Vesicular acetylcholine transporter (VAChT) protein: a novel and unique marker for cholinergic neurons in the central and peripheral nervous systems. Journal of Comparative Neurology 378: 454-67.
