UCHL 1

A neuron specific member of the ubiquitin proteasome system.

General references UCHL 1

Ragland M, Hutter C, Zabetian C & Edwards K (2009). Association between the ubiquitin carboxyl-terminal esterase L1 gene (UCHL1) S18Y variant and Parkinson's Disease: a HuGE review and meta-analysis. American Epidemiology 170: 1344-57.

Xu EH, Tang Y, Li D & Jia JP (2009). Polymorphism of HD and UCHL-1 genes in Huntington's disease. Journal of Clinical Neuroscience 16: 1473-7.

Zhang ZJ, Burgunder JM, An XK, Wu Y, Chen WJ, Zhang JH, Wang YC, Xu YM, Gou YR, Yuan GG, Mao XY & Peng R (2008). Lack of evidence for association of a UCH-L1 S18Y polymorphism with Parkinson's disease in a Han-Chinese population. Neuroscience Letters 442: 200-2.

Hutter CM, Samii A, Factor SA, Nutt JG, Higgins DS, Bird TD, Griffith A, Roberts JW, Leis BC, Montimurro JS, Kay DM, Edwards KL, Payami H & Zabetian CP (2008). Lack of evidence for an association between UCHL1 S18Y and Parkinson's disease. European Journal of Neurology 15: 134-9.

Lombardino AJ, Li XC, Hertel M & Nottebohm F (2005). Replaceable neurons and neurodegenerative disease share depressed UCHL1 levels. Proceedings of the National Academy of Sciences USA 102: 8036-41.

Otsuki T, Yata K, Takata-Tomokuni A, Hyodoh F, Miura Y, Sakaguchi H, Hatayama T, Hatada S, Tsujioka T, Sato Y, Murakami H, Sadahira Y & Sugihara T (2004). Expression of protein gene product 9.5 (PGP9.5)/ubiquitin-C-terminal hydrolase 1 (UCHL-1) in human myeloma cells. British Journal of Haematology 127: 292-8.

Satoh JI & Kuroda Y (2001). Ubiquitin C-terminal hydrolase-L1 (PGP9.5) expression in human neural cell lines following induction of neuronal differentiation and exposure to cytokines, neurotrophic factors or heat stress. Neuropathology and Applied Neurobiology 27: 95-104.

Trowern AR, Laight R, MacLean N & Mann DA (1996). Detection of neuron-specific protein gene product (PGP) 9.5 in the rat and zebrafish using anti-human PGP9.5 antibodies. Neuroscience Letters 210: 21-4.

Day IN (1992). Enolases and PGP9.5 as tissue-specific markers. Biochemical Society Transactions 20: 637-42. no abstract availabe