Tau
A microtubule associated protein
References SySy tau antibodies
Gauthier-Kemper A, Weissmann C, Golovyashkina N, Sebö-Lemke Z, Drewes G, Gerke V, Heinisch JJ & Brandt R (2011). The frontotemporal dementia mutation R406W blocks tau's interaction with the membrane in an annexin A2-dependent manner. Journal of Cell Biology 192: 647-61.
rabbit antibody; WB, ICC
Abe N, Borson SH, Gambello MJ, Wang F & Cavalli V (2010). Mammalian target of rapamycin (mTOR) activation increases axonal growth capacity of injured peripheral nerves. Journal of Biological Chemistry 285: 28034-43.
rabbit antibody; ICC
Rogowski K, van Dijk J, Magiera MM, Bosc C, Deloulme JC, Bosson A, Peris L, Gold ND, Lacroix B, Grau MB, Bec N, Larroque C, Desagher S, Holzer M, Andrieux A, Moutin MJ & Janke C (2010). A family of protein-deglutamylating enzymes associated with neurodegeneration. Cell 143: 564-78.
rabbit antibody; WB
General references tau
Thies E & Mandelkow EM (2007).Missorting of tau in neurons causes degeneration of synapses that can be rescued by the kinase MARK2/Par-1. Journal of Neuroscience 27: 2896-907.
Avila J, Santa-María I, Pérez M, Hernández F & Moreno F (2006). Tau phosphorylation, aggregation, and cell toxicity. Journal of Biomedicine and Biotechnology 2006: 74539.
Duka T, Rusnak M, Drolet RE, Duka V, Wersinger C, Goudreau JL & Sidhu A (2006). Alpha-synuclein induces hyperphosphorylation of Tau in the MPTP model of parkinsonism. FASEB Journal 20: 2302-12.
Black MM, Slaughter T, Moshiach S, Obrocka M & Fischer I (1996). Tau is enriched on dynamic microtubules in the distal region of growing axons. Journal of Neuroscience 16: 3601-19.
Mandell JW & Banker GA (1996). A spatial gradient of tau protein phosphorylation in nascent axons. Journal of Neuroscience 16: 5727-40.
Hirokawa N, Shiomura Y & Okabe S (1988). Tau proteins: the molecular structure and mode of binding on microtubules. Journal of Cell Biology 107: 1449-59.
Connolly JA, Kalnins VI, Cleveland DW & Kirschner MW (1977). Immunoflourescent staining of cytoplasmic and spindle microtubules in mouse fibroblasts with antibody to tau protein. Proceedings of the National Academy of Sciences USA 74: 2437-40.
Witman GB, Cleveland DW, Weingarten MD & Kirschner MW (1976). Tubulin requires tau for growth onto microtubule initiating sites. Proceedings of the National Academy of Sciences USA 73: 4070-4.