Syntaxin 8

A SNARE protein involved in the fusion of late endosomes

References SySy syntaxin 8 antibodies

Madan R, Rastogi R, Parashuraman S & Mukhopadhyay A (2012). Salmonella Acquires Lysosome-associated Membrane Protein 1 (LAMP1) on Phagosomes from Golgi via SipC Protein-mediated Recruitment of Host Syntaxin6. Journal of Biological Chemistry 287: 5574-87. WB

Offenhäuser C, Lei N, Roy S, Collins BM, Stow JL & Murray RZ (2011). Syntaxin 11 binds Vti1b and regulates late endosome to lysosome fusion in macrophages. Traffic 12: 762-73. WB

Flowerdew SE & Burgoyne RD (2009). A VAMP7/Vti1a SNARE complex distinguishes a non-conventional traffic route to the cell surface used by KChIP1 and Kv4 potassium channels. Biochemical Journal 418: 529-40. ICC

Takamori S, Holt M, Stenius K, Lemke EA, Grønborg M, Riedel D, Urlaub H, Schenck S, Brügger B, Ringler P, Müller SA, Rammner B, Gräter F, Hub JS, De Groot BL, Mieskes G, Moriyama Y, Klingauf J, Grubmüller H, Heuser J, Wieland F & Jahn R (2006). Molecular anatomy of a trafficking organelle. Cell 127: 831-46. WB in supplement

Murray RZ, Wylie FG, Khromykh T, Hume DA & Stow JL (2005). Syntaxin 6 and Vti1b form a novel SNARE complex, which is up-regulated in activated macrophages to facilitate exocytosis of tumor necrosis Factor-alpha. Journal of Biological Chemistry 280: 10478-83. WB, IP

Nakamura N, Fukuda H, Kato A & Hirose S (2005). MARCH-II is a syntaxin-6-binding protein involved in endosomal trafficking. Molecular Biology of the Cell 16: 1696-710. WB, ICC

General references syntaxin 8

Antonin W, Dulubova I, Arac D, Pabst S, Plitzner J, Rizo J & Jahn R (2002). The N-terminal domains of syntaxin 7 and vti1b form three-helix bundles that differ in their ability to regulate SNARE complex assembly. Journal of Biological Chemistry 277: 36449-56.

Antonin W, Fasshauer D, Becker S, Jahn R & Schneider TR (2002). Crystal structure of the endosomal SNARE complex reveals common structural principles of all SNAREs. Nature Structural Biology 9: 107-11.

Subramaniam VN, Loh E, Horstmann H, Habermann A, Xu Y, Coe J, Griffiths G & Hong W (2000). Preferential association of syntaxin 8 with the early endosome. Journal of Cell Science 113 (Pt 6): 997-1008.

Antonin W, Holroyd C, Fasshauer D, Pabst S, Von Mollard GF & Jahn R (2000). A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function. EMBO Journal 19: 6453-64.

Prekeris R, Yang B, Oorschot V, Klumperman J & Scheller RH (1999). Differential roles of syntaxin 7 and syntaxin 8 in endosomal trafficking. Molecular Biology of the Cell 10: 3891-908.