Syntaxin 8

A SNARE protein involved in the fusion of late endosomes

General Information

Syntaxin 8, a member of the SNARE family of proteins, is functionally related to the C-terminus of SNAP 25. Syntaxin 8 is localized to endosomal membranes of a wide variety of cells and is involved in the fusion of late endosomes and lysosomes. In endosomal membranes, syntaxin 8 forms complexes with endobrevin, syntaxin 7 and vti1b.