Syntaxin 12/13
A syntaxin family member functioning in the recycling of plasma membrane receptors
References SySy syntaxin 12/13 antibodies
Wang CC, Ng CP, Shi H, Liew HC, Guo K, Zeng Q & Hong W (2010). A role for VAMP8/endobrevin in surface deployment of the water channel aquaporin 2. Molecular and Cellular Biology 30: 333-43
WB
Abe N, Almenar-Queralt A, Lillo C, Shen Z, Lozach J, Briggs SP, Williams DS, Goldstein LS & Cavalli V (2009). Sunday Driver interacts with two distinct classes of axonal organelles. Journal of Biological Chemistry Sep 29. Epub ahead of print.
rabbit antibody; WB, IP, IHC
Takamori S, Holt M, Stenius K, Lemke EA, Grønborg M, Riedel D, Urlaub H, Schenck S, Brügger B, Ringler P, Müller SA, Rammner B, Gräter F, Hub JS, De Groot BL, Mieskes G, Moriyama Y, Klingauf J, Grubmüller H, Heuser J, Wieland F & Jahn R (2006). Molecular anatomy of a trafficking organelle. Cell 127: 831-46.
rabbit antiserum; WB in supplement
Brandhorst D, Zwilling D, Rizzoli SO, Lippert U, Lang T & Jahn R (2006). Homotypic fusion of early endosomes: SNAREs do not determine fusion specificity. Proceedings of the National Acedemy of Sciences USA 103: 2701-6.
Bonanomi D, Menegon A, Miccio A, Ferrari G, Corradi A, Kao HT, Benfenati F & Valtorta F (2005). Phosphorylation of synapsin I by cAMP-dependent protein kinase controls synaptic vesicle dynamics in developing neurons. Journal of Neuroscience 25: 7299-308.
rabbit antiserum; ICC
Vetrivel KS, Cheng H, Lin W, Sakurai T, Li T, Nukina N, Wong PC, Xu H & Thinakaran G (2004). Association of γ-secretase with lipid rafts in post-Golgi and endosome membranes. Journal of Biological Chemistry 279: 44945-54.
rabbit antiserum; WB
Bared SM, Buechler C, Boettcher A, Dayoub R, Sigruener A, Grandl M, Rudolph C, Dada A & Schmitz G (2004). Association of ABCA1 with Syntaxin 13 and Flotillin-1 and enhanced phagocytosis in Tangier cells. Molecular Biology of the Cell 15: 5399-407.
rabbit antiserum; WB, ICC
Riedel D, Antonin W, Fernandez-Chacon R, Alvarez de Toledo G, Jo T, Geppert M, Valentijn JA, Valentijn K, Jamieson JD, Sudhof TC & Jahn R (2002). Rab3D is not required for exocrine exocytosis but for maintenance of normally sized secretory granules. Molecular and Cellular Biology 22: 6487-97.
rabbit antiserum; WB
General references syntaxin 12/13
Antonin W, Holroyd C, Fasshauer D, Pabst S, Fischer Von Mollard G & Jahn R (2000). A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function. EMBO Journal 19: 6453-64.
Jahn R & Sudhof TC (1999). Membrane fusion and exocytosis. Annual Review in Biochemistry 68: 863-911.
Review
Advani RJ, Bae HR, Bock JB, Chao DS, Doung YC, Prekeris R, Yoo JS & Scheller RH (1998). Seven novel mammalian SNARE proteins localize to distinct membrane compartments. Journal of Biological Chemistry 273: 10317-24.
Prekeris R, Klumperman J, Chen YA & Scheller RH (1998). Syntaxin 13 mediates cycling of plasma membrane proteins via tubulovesicular recycling endosomes. Journal of Cell Biology 143: 957-71.