Syntaxin 12/13

A syntaxin family member functioning in the recycling of plasma membrane receptors

General Information

Syntaxin 12/13 are orthologues of the same gene whose product is a member of the SNARE family of proteins. It is related to syntaxins 1-4 but is localized predominantly to early endosomes of a wide variety of cells. Syntaxin 12/13 appears to be involved in the recycling of membrane receptors such as the transferrin receptors where it mediates the fusion of endosomal membranes.