Syntaxin 11

A SNARE protein abundantly expressed in the immune system

General references syntaxin 11

zur Stadt U, Rohr J, Seifert W, Koch F, Grieve S, Pagel J, Strauss J, Kasper B, Nürnberg G, Becker C, Maul-Pavicic A, Beutel K, Janka G, Griffiths G, Ehl S & Hennies HC (2009). Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11. American Journal of Human Genetics 85: 482-92.

Arneson LN, Brickshawana A, Segovis CM, Schoon RA, Dick CJ & Leibson PJ (2007). Cutting edge: syntaxin 11 regulates lymphocyte-mediated secretion and cytotoxicity. Journal of Immunology 179: 3397-401.

Bryceson YT, Rudd E, Zheng C, Edner J, Ma D, Wood SM, Bechensteen AG, Boelens JJ, Celkan T, Farah RA, Hultenby K, Winiarski J, Roche PA, Nordenskjöld M, Henter JI, Long EO & Ljunggren HG (2007). Defective cytotoxic lymphocyte degranulation in syntaxin-11 deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients. Blood 110: 1906-15.

Prekeris R, Klumperman J & Scheller RH (2000). Syntaxin 11 is an atypical SNARE abundant in the immune system. European Journal of Cell Biology 79: 771-80.

Valdez AC, Cabaniols JP, Brown MJ & Roche PA (1999). Syntaxin 11 is associated with SNAP-23 on late endosomes and the trans-Golgi network. Journal of Cell Science 112(Pt 6): 845-54.

Advani RJ, Bae HR, Bock JB, Chao DS, Doung YC, Prekeris R, Yoo JS & Scheller RH (1998). Seven novel mammalian SNARE proteins localize to distinct membrane compartments. Journal of Biological Chemistry 273: 10317-24.