Syntaxin 11

A SNARE protein abundantly expressed in the immune system

General Information

Syntaxin 11, a member of the SNARE family of proteins, localizes to late endosomes and the trans-Golgi network and has been shown to interact with VAMP proteins and SNAP 23. Unlike other syntaxins it does not possess a carboxy-terminal transmembrane anchor.
In the immune systems several cell types like phagocytic immune cells, resting natural killer (NK) cells and CD8-T-cells express syntaxin 11. High levels of protein can also be found in lung and placenta but not in brain where it is almost undetectable.