Syntaxin 1

Plasma membrane protein essential for synaptic vesicle fusion

References SySy syntaxin 1 antibodies

Lazarevic V, Schöne C, Heine M, Gundelfinger ED & Fejtova A (2011). Extensive remodeling of the presynaptic cytomatrix upon homeostatic adaptation to network activity silencing. Journal of Neuroscience 31: 10189-200. Clone 78.3; WB

Kabayama H, Takeuchi M, Taniguchi M, Tokushige N, Kozaki S, Mizutani A, Nakamura T & Mikoshiba K (2011). Syntaxin 1B Suppresses Macropinocytosis and Semaphorin 3A-Induced Growth Cone Collapse. Journal of Neuroscience 31: 7357-7364. syntaxin 1B rabbit antibody; WB

Jiang X, Litkowski PE, Taylor AA, Lin Y, Snider BJ & Moulder KL (2010). A role for the ubiquitin-proteasome system in activity-dependent presynaptic silencing. Journal of Neuroscience 30: 1798-1809. Clone 78.3; ICC

Nagy G, Milosevic I, Mohrmann R, Wiederhold K, Walter AM & Sørensen JB (2008). The SNAP-25 linker as an adaptation toward fast exocytosis. Molecular Biology of the Cell 19: 3769-81. Syntaxin 1A rabbit antiserum; ICC

Barszczewski M, Chua JJ, Stein A, Winter U, Heintzmann R, Zilly FE, Fasshauer D, Lang T & Jahn R (2008). A novel site of action for alpha-SNAP in the SNARE conformational cycle controlling membrane fusion. Molecular Biology of the Cell 19: 776-84. Clone 78.3; ICC

Jockusch WJ, Speidel D, Sigler A, Sørensen JB, Varoqueaux F, Rhee JS & Brose N (2007). CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins. Cell 131: 796-808. Clone 78.2; WB in supplement

Smith R, Klein P, Koc-Schmitz Y, Waldvogel HJ, Faull RL, Brundin P, Plomann M & Li JY (2007). Loss of SNAP-25 and rabphilin 3a in sensory-motor cortex in Huntington's disease. Journal of Neurochemistry 103: 115-23. Clone 78.2; WB, IHC

Bilan F, Thoreau V, Nacfer M, Dérand R, Norez C, Cantereau A, Garcia M, Becq F & Kitzis A (2004). Syntaxin 8 impairs trafficking of cystic fibrosis transmembrane conductance regulator (CFTR) and inhibits its channel activity. Journal of Cell Science 117(Pt10): 1923-35. Clone 78.3; WB, ICC

Hatsuzawa K, Lang T, Fasshauer D, Bruns D & Jahn R (2003). The R-SNARE motif of tomosyn forms SNARE core complexes with syntaxin 1 and SNAP-25 and down-regulates exocytosis. Journal of Biological Chemistry 278: 31159-66. Clone 78.3; WB, ICC

von Kriegstein K & Schmitz F (2003). The expression pattern and assembly profile of synaptic membrane proteins in ribbon synapses of the developing mouse retina. Cell Tissue Research 311: 159-73. Clone 78.2; IHC

Martinez-Arca S, Proux-Gillardeaux V, Alberts P, Louvard D & Galli T (2003). Ectopic expression of syntaxin 1 in the ER redirects TI-VAMP- and cellubrevin-containing vesicles. Journal of Cell Science 116: 2805-16. Syntaxin 1A rabbit antiserum; WB, ICC

Low SH, Marmorstein LY, Miura M, Li X,Kudo N, Marmorstein AD & Weimbs T (2002). Retinal pigment epithelial cells exhibit unique expression and localization of plasma membrane syntaxins which may contribute to their trafficking phenotype. Journal of Cell Science 115: 4545-53. Syntaxin 1B rabbit antiserum; WB, IHC

Kubota S, Kobayashi A, Mori N, Higashide T, McLaren MJ & Inana G (2002). Changes in retinalsSynapticpProteins in the transgenic model expressing a mutant HRG4 (UNC119). Investigative Ophthalmology & Visual Science 43: 308-13. Syntaxin 1B rabbit antiserum; IHC

Varoqueaux F, Sigler A, Rhee JS, Brose N, Enk C, Reim K & Rosenmund C (2002). Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming. Proceedings of the National Academy of Sciences USA 99: 9037-42. Clone 78.3; WB

von Kriegstein K, Schmitz F, Link E & Sudhof T (1999). Distribution of synaptic vesicle proteins in the mammalian retina identifies obligatory and facultative components of ribbon synapses. European Journal of Neuroscience 11: 1335-48. Clone 78.2; WB, IHC

General references syntaxin 1

Lin RC & Scheller RH (2000). Mechanisms of synaptic vesicle exocytosis. Annual Reviews of Cell and Developmental Biology 16: 19-49. Review

Foletti DL, Lin R, Finley MA & Scheller RH (2000). Phosphorylated syntaxin 1 is localized to discrete domains along a subset of axons. Journal of Neuroscience 20: 4535-44.

Jahn R & Südhof TC (1999). Membrane fusion and exocytosis. Annual Review of Biochemistry 68: 863-911. Review

Südhof TC (1995). The synaptic vesicle cycle: a cascade of protein-protein interactions. Nature 375: 645-53. Review

Jahn R & Südhof TC (1994). Synaptic vesicles and exocytosis. Annual Review of Neuroscience 17: 219-46. Review, no abstract available

Bennett MK, Calakos N & Scheller RH (1992). Syntaxin: a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones. Science 257: 255-9.

Inoue A, Obata K & Akagawa K (1992). Cloning and sequence analysis of cDNA for a neuronal cell membrane antigen, HPC-1. Journal of Biological Chemistry 267: 10613-9.

Hirai Y, Takebe K, Takashina M, Kobayashi S & Takeichi M (1992). Epimorphin: a mesenchymal protein essential for epithelial morphogenesis. Cell 69: 471-81.

Barnstable CJ, Hofstein R & Akagawa K (1985). A marker of early amacrine cell development in rat retina. Brain Research 352: 286-90.